Emergence of drug-resistant HIV-1 after intrapartum administration of single-dose nevirapine is substantially underestimated
JA Johnson, J Li, L Morris, N Martinson…�- The Journal of�…, 2005 - academic.oup.com
Conventional sequence analysis detects human immunodeficiency virus (HIV)–1 drug
resistance mutations in∼ 40% of women shortly after they receive intrapartum single-dose�…
resistance mutations in∼ 40% of women shortly after they receive intrapartum single-dose�…
Persistence of nevirapine-resistant HIV-1 in women after single-dose nevirapine therapy for prevention of maternal-to-fetal HIV-1 transmission
S Palmer, V Boltz, N Martinson…�- Proceedings of the�…, 2006 - National Acad Sciences
Single-dose nevirapine (sdNVP) for prevention of mother-to-child transmission of HIV-1 can
select nevirapine (NVP)-resistant variants, but the frequency, duration, and clinical�…
select nevirapine (NVP)-resistant variants, but the frequency, duration, and clinical�…
Development of resistance mutations in women receiving standard antiretroviral therapy who received intrapartum nevirapine to prevent perinatal human�…
CK Cunningham, ML Chaix…�- The Journal of�…, 2002 - academic.oup.com
Abstract Pediatric AIDS Clinical Trials Group protocol 316 was an international, multicenter,
placebo-controlled trial comparing single-dose oral nevirapine (200 mg to mother and 2�…
placebo-controlled trial comparing single-dose oral nevirapine (200 mg to mother and 2�…
Nevirapine (NVP) resistance in women with HIV-1 subtype C, compared with subtypes A and D, after the administration of single-dose NVP
SH Eshleman, DR Hoover, S Chen…�- The Journal of�…, 2005 - academic.oup.com
Abstract Objective In the Human Immunodeficiency Virus (HIV) Network for Prevention Trials
(HIVNET) 012 trial in Uganda, 6–8 weeks after single-dose nevirapine (SD-NVP), NVP�…
(HIVNET) 012 trial in Uganda, 6–8 weeks after single-dose nevirapine (SD-NVP), NVP�…
Comparison of nevirapine (NVP) resistance in Ugandan women 7 days vs. 6–8 weeks after single-dose NVP prophylaxis: HIVNET 012
SH Eshleman, LA Guay, A Mwatha…�- AIDS research and�…, 2004 - liebertpub.com
We compared nevirapine (NVP) resistance (NVPR) mutations in maternal plasma 7 days vs.
6–8 weeks after single-dose NVP prophylaxis. In the HIVNET 012 trial, Ugandan women�…
6–8 weeks after single-dose NVP prophylaxis. In the HIVNET 012 trial, Ugandan women�…
[HTML][HTML] Intrapartum exposure to nevirapine and subsequent maternal responses to nevirapine-based antiretroviral therapy
G Jourdain, N Ngo-Giang-Huong…�- …�England Journal of�…, 2004 - Mass Medical Soc
Background A single intrapartum dose of nevirapine for the prevention of mother-to-child
transmission of human immunodeficiency virus (HIV) leads to the selection of resistance�…
transmission of human immunodeficiency virus (HIV) leads to the selection of resistance�…
Persistent minority K103N mutations among women exposed to single-dose nevirapine and virologic response to nonnucleoside reverse-transcriptase inhibitor�…
A Coovadia, G Hunt, EJ Abrams…�- Clinical infectious�…, 2009 - academic.oup.com
Objective. We investigated whether there are long-lasting effects of exposure to single-dose
nevirapine (sdNVP) treatment on virologic response to nonnucleoside reverse-transcriptase�…
nevirapine (sdNVP) treatment on virologic response to nonnucleoside reverse-transcriptase�…
Sensitive drug-resistance assays reveal long-term persistence of HIV-1 variants with the K103N nevirapine (NVP) resistance mutation in some women and infants�…
T Flys, DV Nissley, CW Claasen, D Jones…�- The Journal of�…, 2005 - academic.oup.com
Abstract Background The HIV Network for Prevention Trials (HIVNET) 012 trial showed that
NVP resistance (NVPR) emerged in some women and children after the administration of�…
NVP resistance (NVPR) emerged in some women and children after the administration of�…
Distinct patterns of emergence and fading of K103N and Y181C in women with subtype A vs. D after single-dose nevirapine: HIVNET 012
SH Eshleman, LA Guay, J Wang…�- JAIDS Journal of�…, 2005 - journals.lww.com
Background: The HIVNET 012 trial in Uganda demonstrated that single-dose nevirapine
(NVP) can prevent HIV-1 mother-to-child transmission. NVP resistance (NVPR) mutations�…
(NVP) can prevent HIV-1 mother-to-child transmission. NVP resistance (NVPR) mutations�…
Resistance after single-dose nevirapine prophylaxis emerges in a high proportion of Malawian newborns
SH Eshleman, DR Hoover, S Chen, SE Hudelson…�- Aids, 2005 - journals.lww.com
The administration of single-dose nevirapine to women in labor and their infants can prevent
HIV-1 mother-to-child transmission. We examined nevirapine resistance in infants who were�…
HIV-1 mother-to-child transmission. We examined nevirapine resistance in infants who were�…