Stress is a well‐known risk factor in the development of addiction and in addiction relapse
vulnerability. A series of population‐based and epidemiological studies have identified�…

Stress is one of the most commonly reported precipitants of drug use and is considered the
number one cause of relapse to drug abuse. For the past several decades, there have been�…

Rationale: The notion that stress leads to drug abuse in vulnerable individuals and relapse
in addicts is not new. Most major theories of addiction postulate that stress plays an�…

This review provides a neuroadaptive perspective regarding the role of the hormonal and
brain stress systems in drug addiction with a focus on the changes that occur during the�…

A growing clinical literature indicates that there is a link between substance abuse and
stress. One explanation for the high co-occurrence of stress-related disorders and drug�…

Childhood trauma and post-childhood chronic/repeated stress could increase the risk of a
substance use disorder by affecting five stages of addiction illness-course:(a) initial�…

A number of studies have assessed the effects of psychoactive drugs on stress biology, the
neuroadaptations resulting from chronic drug use on stress biology, and their effects on�…

ABSTRACT A challenging question that continues unanswered in the field of addiction is
why some individuals are more vulnerable to substance use disorders than others�…

Sustained exposure to various psychological stressors can exacerbate neuropsychiatric
disorders, including drug addiction. Addiction is a chronic brain disease in which individuals�…

It is well known that stress is a significant risk factor for the development of drug addiction
and addiction relapse. Remarkably, the cognitive processes involved in the effects of stress�…