Evaluating the information content of shallow shotgun metagenomics
Although microbial communities are associated with human, environmental, plant, and
animal health, there exists no cost-effective method for precisely characterizing species and�…
animal health, there exists no cost-effective method for precisely characterizing species and�…
[HTML][HTML] Shallow shotgun sequencing reduces technical variation in microbiome analysis
AJ La Reau, NB Strom, E Filvaroff, K Mavrommatis…�- Scientific reports, 2023 - nature.com
The microbiome is known to play a role in many human diseases, but identifying key
microbes and their functions generally requires large studies due to the vast number of�…
microbes and their functions generally requires large studies due to the vast number of�…
[HTML][HTML] Characterization of shallow whole-metagenome shotgun sequencing as a high-accuracy and low-cost method by complicated mock microbiomes
W Xu, T Chen, Y Pei, H Guo, Z Li, Y Yang…�- Frontiers in�…, 2021 - frontiersin.org
Characterization of the bacterial composition and functional repertoires of microbiome
samples is the most common application of metagenomics. Although deep whole�…
samples is the most common application of metagenomics. Although deep whole�…
[HTML][HTML] Benchmarking second and third-generation sequencing platforms for microbial metagenomics
Shotgun metagenomic sequencing is a common approach for studying the taxonomic
diversity and metabolic potential of complex microbial communities. Current methods�…
diversity and metabolic potential of complex microbial communities. Current methods�…
Quantitative assessment of shotgun metagenomics and 16S rDNA amplicon sequencing in the study of human gut microbiome
I Laudadio, V Fulci, F Palone, L Stronati…�- OMICS: A Journal of�…, 2018 - liebertpub.com
The analysis of microbiota composition in humans, animals, and built environments is
important because of emerging roles and applications in a broad range of disease and�…
important because of emerging roles and applications in a broad range of disease and�…
[HTML][HTML] MetaWRAP—a flexible pipeline for genome-resolved metagenomic data analysis
Background The study of microbiomes using whole-metagenome shotgun sequencing
enables the analysis of uncultivated microbial populations that may have important roles in�…
enables the analysis of uncultivated microbial populations that may have important roles in�…
Shotgun metagenomics, from sampling to analysis
Diverse microbial communities of bacteria, archaea, viruses and single-celled eukaryotes
have crucial roles in the environment and in human health. However, microbes are�…
have crucial roles in the environment and in human health. However, microbes are�…
[HTML][HTML] Toward accurate and quantitative comparative metagenomics
S Nayfach, KS Pollard�- Cell, 2016 - cell.com
Shotgun metagenomics and computational analysis are used to compare the taxonomic and
functional profiles of microbial communities. Leveraging this approach to understand roles of�…
functional profiles of microbial communities. Leveraging this approach to understand roles of�…
[PDF][PDF] Assessment of fecal DNA extraction protocols for metagenomic studies
Background Shotgun metagenomic sequencing has improved our understanding of the
human gut microbiota. Various DNA extraction methods have been compared to find�…
human gut microbiota. Various DNA extraction methods have been compared to find�…
Accessible, curated metagenomic data through ExperimentHub
To the Editor: The microbiome has emerged as a key aspect of human biology and has been
implicated in many disease etiologies. Shotgun metagenomic sequencing is an approach�…
implicated in many disease etiologies. Shotgun metagenomic sequencing is an approach�…