Inhibin and activin: their roles in ovarian tumorigenesis and their diagnostic utility in surgical pathology practice

W Zheng, SC Lauchlan�- Applied Immunohistochemistry &�…, 1999 - journals.lww.com
… of both ovarian epithelial … inhibin and activin and their tissue distribution. We present the
current opinion regarding the function of both inhibin and activin in the development of ovarian

Role of the inhibin/activin system and luteinizing hormone in adrenocortical tumorigenesis

F Beuschlein, BD Looyenga, M Reincke…�- Hormone and�…, 2004 - thieme-connect.com
… The absence of inhibin induces spontaneous ovarian tumorigenesis by as yet undefined …
with pronounced ovarian tumor growth leading to high levels of circulating activin (D). …

Activin and inhibin, estrogens and NFκB, play roles in ovarian tumourigenesis is there crosstalk?

AE Drummond, PJ Fuller�- Molecular and cellular endocrinology, 2012 - Elsevier
… To date, little is known about the capacity of NFκB to influence normal ovarian function … the
roles that inhibin/activin, estrogen and NFκB, have been attributed within carcinogenesis and …

Activins and inhibins in endocrine and other tumors

GP Risbridger, JF Schmitt, DM Robertson�- Endocrine reviews, 2001 - academic.oup.com
… , and role of activin and inhibin in endocrine tumorigenesis, including … that both inhibin and
activin contribute to tumorigenesis. … of activin within the transplanted inhibin-deficient ovaries

Presence of activin, inhibin, and follistatin in epithelial ovarian carcinoma

CK Welt, G Lambert-Messerlian…�- The Journal of�…, 1997 - academic.oup.com
activin results in tumorigenesis. A recent study of six human epithelial ovarian cancer cell
lines revealed absence of inhibin … , and the presence of the activin type II receptor and βA and/…

Inhibin/activin and ovarian cancer.

DM Robertson, HG Burger…�- Endocrine-related�…, 2004 - erc.bioscientifica.com
ovarian tumour suppressor. This review examines the localisation and expression of the
inhibin/activin subunits in the various ovarian … Smad4 may have a role in ovarian tumorigenesis. …

The inhibin/activin family and ovarian cancer

HG Burger, PJ Fuller�- Trends in Endocrinology & Metabolism, 1996 - cell.com
… These data suggest that repeated ovulation and/or continued stimulation of the ovarian
epithelium may be important factors in tumorigenesis. An understanding of the molecular …

Immunohistochemical localization of inhibin and activin subunits in human epithelial ovarian tumors

K Yamashita, M Yamoto, T Shikone, S Minami…�- American journal of�…, 1999 - Elsevier
… of activins, or both, might be involved in ovarian tumorigenesis and, together with our findings,
that inhibins might be defensive, whereas activins … for cell proliferation in ovarian tumors. …

Tumor stroma as the main source of inhibin production in ovarian epithelial tumors

W Zheng, JJ Lu, F Luo, J Hsieh…�- American Journal of�…, 2000 - Wiley Online Library
… Despite significant research efforts, the mechanisms of ovarian tumorigenesis remain … ,
suggest that inhibins and activins are involved in ovarian tumorigenesis.Inhibin and activin are …

Inhibin and activin are demonstrable by immunohistochemistry in ovarian tumor tissue

CJ Gurusinghe, DL Healy, T Jobling, P Mamers…�- Gynecologic�…, 1995 - Elsevier
ovarian tumors indeed do contain inhibin and activin inunoreactivity, consistent with the
possibility that these peptides may be secreted in excess in ovarian … involved in tumorigenesis. …