[HTML][HTML] Lung cancer genomic signatures

MT Agull�-Ortu�o, F L�pez-R�os, L Paz-Ares�- Journal of Thoracic Oncology, 2010 - Elsevier
Lung cancer (LC) is the dominant cause of death by cancer in the world, being responsible
for more than a million deaths annually. It is a highly lethal common tumor that is frequently …

Integrating genomic features for non-invasive early lung cancer detection

JJ Chabon, EG Hamilton, DM Kurtz, MS Esfahani…�- Nature, 2020 - nature.com
… ‘lung cancer likelihood in plasma’ (Lung-CLiP), which can robustly discriminate early-stage
lung cancer … Our findings establish the potential of cfDNA for lung cancer screening and …

[HTML][HTML] Somatic genomics and clinical features of lung adenocarcinoma: a retrospective study

J Shi, X Hua, B Zhu, S Ravichandran, M Wang…�- PLoS�…, 2016 - journals.plos.org
… performed integrative genomic analysis based on a set of lung cancer patients and had no
prospective clinical protocol or analysis plan. The associations between genomic features (…

[HTML][HTML] Genomic features of response to combination immunotherapy in patients with advanced non-small-cell lung cancer

MD Hellmann, T Nathanson, H Rizvi, BC Creelan…�- Cancer cell, 2018 - cell.com
… promising benefit in lung cancer, but predictors of response to combination therapy are
unknown. Using whole-exome sequencing to examine non-small-cell lung cancer (NSCLC) …

Association of patient characteristics and tumor genomics with clinical outcomes among patients with non–small cell lung cancer using a clinicogenomic database

G Singal, PG Miller, V Agarwala, G Li, G Kaushik…�- Jama, 2019 - jamanetwork.com
cancers were analyzed separately given the well-established differences in mutational
landscape between these tumor types. The genomic … and squamous cell lung cancers. For …

[HTML][HTML] Multiple primary lung cancer: Updates of clinical management and genomic features

H Tian, G Bai, Z Yang, P Chen, J Xu, T Liu, T Fan…�- Frontiers in�…, 2023 - frontiersin.org
Genomic updates about MPLC Genomic characteristics of multifocal lung cancer started
over 25 years ago (64). With the development of science and technology and the progress of …

Multimodal genomic features predict outcome of immune checkpoint blockade in non-small-cell lung cancer

V Anagnostou, N Niknafs, K Marrone, DC Bruhm…�- Nature cancer, 2020 - nature.com
… We then assessed correlations among genomic and immune features and identified four
clusters of inter-correlated features centered on RTK mutations, HLA genetic variation, tumor …

A prediction model for lung cancer diagnosis that integrates genomic and clinical features

J Beane, P Sebastiani, TH Whitfield, K Steiling…�- Cancer Prevention�…, 2008 - AACR
… the diagnostic evaluation of patients with suspect lung cancer. Determining which suspect
lung cancer patients with lung cancer-negative bronchoscopies should undergo these …

[HTML][HTML] Clinical and genomic features of Chinese lung cancer patients with germline mutations

W Peng, B Li, J Li, L Chang, J Bai, Y Yi, R Chen…�- Nature�…, 2022 - nature.com
… The germline mutation landscape in Chinese lung cancer patients has not been well
defined. In this study, sequencing data of 1,021 cancer genes of 1,794 Chinese lung cancer

[HTML][HTML] Genomic features of Chinese small cell lung cancer

J Liu, Z Zhao, S Wei, B Li, Z Zhao�- BMC Medical Genomics, 2022 - Springer
… In this study, we investigated the genomic features of Chinese SCLC patients. … cancer that
kills ~ 250,000 people worldwide annually and accounts for approximately 15% of lung cancer