… Great advances in immune checkpoint blockade have resulted in a paradigm shift in patients
with lung cancer. Immune-checkpoint inhibitor (ICI) treatment, either as monotherapy or …

… This review focuses on the mechanisms of action of the main checkpoint inhibitors in lung
cancer and presents the most relevant results from preclinical and clinical studies on immune-…

… -small cell lung cancer (NSCLC) has been revolutionized by the introduction of immune
checkpoint … Studies investigating lung cancer from the perspective of TME pointed out a complex …

… Although EGFR mutant tumors exhibit low response rates to immune checkpoint blockade
… the characteristics of EGFR mutant lung tumors responsive to immune checkpoint blockade. …

… cases of lung cancer and an estimated 158,040 lung cancer deaths … lung cancer (NSCLC)
and small cell lung cancer (SCLC) (Siegel et al., 2015). Therapeutic advances for lung cancer …

… immune checkpoint blockade in metastatic lung cancer patients (… with early-stage non–small
cell lung cancer (N = 14), where … response to immune checkpoint blockade. These analyses …

… and natural history of advanced non-small cell lung cancer (NSCLC) have been
revolutionised. Indeed, the benefit of immune checkpoint inhibitors (ICIs) over previously standard …

… cell lung cancer (NSCLC). Here, we examine the rationale for targeting immune checkpoints
in lung cancer and review the clinical data from studies with immune checkpoint inhibitors …

… checkpoint inhibitors and cancer vaccines, have changed the treatment strategy for some
types of cancer… In this review, we present the data on immune checkpoint blockade for NSCLC, …

… of immune therapy ('immune checkpoint blockade—ICB'). … Lung cancer is still the malignancy
with the highest mortality … for 80%-85% of all lung cancer cases. An estimated 60% of …