Maternal plasma adrenocorticotropin and cortisol relationships throughout human pregnancy

…, CR Parker Jr, JD Madden, PC MacDonald…�- American journal of�…, 1981 - Elsevier
Adrenocorticotropin (ACTH) and cortisol in plasma were measured weekly from early in
gestation through delivery in five women whose pregnancies were normal. During the twelfth …

Aromatization of androstenedione by human adipose tissue stromal cells in monolayer culture

…, CR MENDELSON, PC MACDONALD…�- The Journal of�…, 1981 - academic.oup.com
Stromal cells and adipocytes were separated after collagenase treatment of adipose tissue
obtained from women undergoing elective surgery, and these cells were used to study …

A clinical test useful for predicting the development of acute hypertension in pregnancy

…, PJ Whalley, UD Crosby, PC MacDonald�- American journal of�…, 1974 - Elsevier
Ninety-three per cent of nulliparous, normotensive young women who subsequently developed
pregnancy-induced hypertension demonstrated an increase in diastolic blood pressure …

Plasma Precursors of Estrogen. I. Extent of Conversion of Plasma Δ4-Androstenedione to Estrone in Normal Males and Nonpregnant Normal, Castrate and�…

PC MACDONALD, RP ROMBAUT…�- The Journal of Clinical�…, 1967 - academic.oup.com
… t Each subject (except WC and PM-2) received a tracer dose of between 8.5 and 26.2 pc
of 4-14C-A4androstenedione together with between 2.13 and 8.0 uc of 6,7-3H-estrone. WC …

Cachectin/tumor necrosis factor-alpha formation in human decidua. Potential role of cytokines in infection-induced preterm labor.

…, B Beutler, L Milewich, PC MacDonald�- The Journal of�…, 1989 - Am Soc Clin Investig
This study was conducted as part of an investigation to evaluate the hypothesis that bacterial
toxins (LPS or lipoteichoic acid), acting on macrophage-like uterine decidua to cause …

Initiation of human parturition: XII. Biosynthesis and metabolism of prostaglandins in human fetal membranes and uterine decidua

T Okazaki, ML Casey, JR Okita, PC MacDonald…�- American Journal of�…, 1981 - Elsevier
Prostaglandin synthetase activity was assayed in homogenates prepared from human fetal
membranes and uterine decidua tissues with [ 14 C]arachidonic acid used as substrate. In …

17 beta-Hydroxysteroid dehydrogenase type 2: chromosomal assignment and progestin regulation of gene expression in human endometrium.

ML Casey, PC MacDonald…�- The Journal of clinical�…, 1994 - Am Soc Clin Investig
The cDNAs for two separate human 17 beta-hydroxysteroid dehydrogenases (17 beta-HSD)
have been isolated and sequenced. The well-studied human placental cytosolic 17 beta-…

Effect of obesity on conversion of plasma androstenedione to estrone in ovulatory and anovulatory young women

CD Edman, PC MacDonald�- American journal of obstetrics and�…, 1978 - Elsevier
The purpose of this study was to evaluate the transfer constant of conversion of plasma
androstenedione to estrone ([ϱ] BU AE1 ) as a function of total body weight and excess body …

The utilization of circulating dehydroisoandrosterone sulfate for estrogen synthesis during human pregnancy

PK Siiteri, PC MacDonald�- Steroids, 1963 - Elsevier
Estrogen biosynthesis during human pregnancy has been studied by examination of the
radioactive urinary metabolites excreted following the intravenous administration of isotope-…

Interstitial collagen synthesis and processing in human amnion: a property of the mesenchymal cells

M Linette Casey, PC MacDonald�- Biology of reproduction, 1996 - academic.oup.com
This study was conducted to evaluate the ontogeny and cellular site of interstitial collagen
formation in amnion, the tissue that provides the tensile strength of the human fetal membranes…