… In the presence of arachidonic (10-s mol/L) or linoleic acids (10-• mol/L) in serum-free
medium, the addition of dexamethasone (10-• mol/L) or cortisol (10- 1 mol/L) suppressed but did …

A tumour of the left adrenal gland was identified in a woman who presented with virilization
and secondary amenorrhea. Preoperatively, the plasma levels of dehydroepiandrosterone …

… of 17/?-hydroxy-l,4-androstadien-3-one (Brodie, Hayano & Gut, … carried out as previously
described (Milewich & Axelrod, … chromatograms for carrying out colour reactions (Milewich & …

… Frenkel RA, Slaughter CA, Orth K., Moomaw CR, Hicks SH, Snyder JM, Bennett M., Prough
RA, Putnam RS and Milewich L.: Peroxisome proliferation and induction of peroxisomal …

… This was accomplished by the stereospecific reaction (l) of 17~-bromopregnenolone (2)
with zinc metal dust and tritiated acetic acid (CH,C0,… 1,730 (acetates C = 0), 1,269 cm-l (C-0-C); …

The reaction of 3^-hydroxy-21-formylpregn-5-en-20-one sodium enolate (7) with
hydroxylamine hydrochloride, in ethanol-water, gave 3^-hydroxy-21-formyl-22-oximinopregn-5-en-20-…

Recent in-vitro studies made by Askari, Monette & Leroux (1970), concerning the synthesis
of C 19 steroids by the adrenal gland of male and female rats, indicate that androstenedione, …

… Substrate saturation kinetics were determined with steroid concentrations in the range of l-60
PM for DHIA and I-100 PM for And. Propylene glycol (50 ~1) was added to dissolve the …

The cell line designated as A431 is characterized by an extraordinary capacity for binding of
epidermal growth factor (EGF); but paradoxically, these cells also are characterized by …