Dietary dehydroepiandrosterone (DHEA) reduces food intake in mice, and this response is
under genetic control. Moreover, both food restriction and DHEA can prevent or ameliorate …

Infusions of dehydroepiandrosterone (D) into pregnant ewes result in increased maternal
plasma concentrations of estrone and estradiol. To investigate the role of the ovine …

We studied the effect of transforming growth factor-β (TGF-β) on prostaglandin E 2 (PGE 2 )
production and mitogenesis in human amnion cells and compared the response in amnion …

We present data pertaining to some of the in vivo effects associated with dietary DHEA
administration to mice and rats. Dietary DHEA leads to:(1) decrease in body weight gain;(2) …

In the steroidogenic pathway, 3β-hydroxysteroid dehydrogenase-isomerase (3βHSD) catalyzes
the formation of hormonally active Δ 4 -3-ketosteroids from Δ 5 -3β-hydroxysteroids. In …

… Since the pattern of steroid secretion during the first week in organ culture may better
represent the pattern of steroid secretion in vivo than that observed in cultures older than L -week, …

The properties of human fetal liver (HFL) estrogen 16α-hydroxylase (16α-0Hase) were studied
in microsomal preparations and hepatocytes maintained in culture. A specific assay was …

The carbon‐14 labelled steroids, androsterone‐4‐ 14 C, isoandrosterone‐4‐ 14 C, 5α‐androstanedione‐4‐
14 C, 5α‐androstane‐3β, 17β‐diol‐4‐ 14 C, and 5α‐androstane‐3α, 17β‐…

Dehydroepiandrosterone (DHEA) treatment is effective in preventing or delaying the onset
of various genetic and induced disorders of mice and rats. Associated with the beneficial …

Both dietary dehydroepiandrosterone (DHEA) and food restriction can prevent or modulate
the initiation or progression of a number of diseases in rodents and prolong life span. We …