A decreased rate of progesterone metabolism is detected in human fetal membranes
several weeks preceding normal parturition at term. A 10-to 20-fold decrease in 20 [alpha]-…

The regulation of both the activity of 3-hydroxy-3-methyl glutaryl coenzyme A (HMG CoA)
reductase [mevalonate-NADP + oxidoreductase (CoA-acylating) EC 1.1.1.34] and the secretion …

In this investigation the metabolism of 1,4-androstadiene-3,17-dione by human placental
microsomes was evaluated. The experiments were conducted with the substrate [ 3 H]-1,4-…

In this investigation, the metabolism of [7- 3 HN]pregnenolone and [7- 3 HN]progesterone
by slices of normal human lung tissue was evaluated. Employing a combination of …

… gelatin in phosphate-buffered saline containing approximately 10,000 dpm [l,2,6,7-3H]…
George, FW, L. Milewich, and JD Wilson. Oestrogen content of the embryonic rabbit ovary, …

… androsterone, and isoandrosterone [l]. The lung is continually exposed to hormones in
circulation and, thus, may participate in peripheral activation and inactivation of blood-borne …

… The specific activity of midterm fetal liver microsomal I7floHSOR is relatively high and is
similar to that of the midterm human placental microsomal enzyme (Milewich, MacDonald and …

ALTHOUGH the essential role of endocrine function of the fetal testis for male phenotypic
development is established 1–3 , endocrine function of the fetal ovary is not thought to be …

… Milewich L, Parker PS, MacDonald PC 1978 Testosterone metabolism by human lung tissue.
J Steroid Biochem 9:29 7. Martini L … Milewich L, Schweikert HU 1977 Synthesis of carbon-…

… /L, 13 /iCi) or DHEAS (15 /�mol/L, 12mC�) in 1 mL of TRIS buffer (0.1 mol/L; pH, 7.4) in the
presence of glucose (5.6 mmol/L) at … Milewich L, Garcia RL. Steroid sulfatase activity in amnion …