Steroid 5α-reductase activity in endothelial cells from human umbilical cord vessels
L Milewich, V Kaimal, AR Johnson�- Journal of steroid biochemistry, 1987 - Elsevier
… glycol as described previously [l]; and, aliquots (l/10) of the fractions collected were assayed
for radioactivity by scintillation spectrometry. The counting efficiency for tritium was 40% and …
for radioactivity by scintillation spectrometry. The counting efficiency for tritium was 40% and …
Metabolism of androstenedione by human platelets: a source of potent androgens
L MILEWICH, MG WHISENANT�- The Journal of Clinical�…, 1982 - academic.oup.com
The metabolism of tritium-labeled androstenedione by human platelets was studied in vitro.
The following metabolites were identified: testosterone, 5α-androstane-3,17-dione, …
The following metabolites were identified: testosterone, 5α-androstane-3,17-dione, …
Steroid sulfatase and 17β-hydroxysteroid oxidoreductase activities in mouse tissues
L Milewich, RL Garcia, LW Gerrity�- Journal of steroid biochemistry, 1984 - Elsevier
The metabolism of estrone sulfate and dehydroisoandrosterone sulfate to the free, unconjugated
steroids, estrone and dehydroisoandrosterone, was demonstrated in more than thirty …
steroids, estrone and dehydroisoandrosterone, was demonstrated in more than thirty …
Activity of 17β-hydroxysteroid oxidoreductase in tissues of the human fetus
L Milewich, PC MacDonald…�- Journal of endocrinology, 1989 - joe.bioscientifica.com
The interconversion of oestrone and oestradiol, androstenedione and testosterone, and
dehydroepi-androsterone and 5-androstene-3β,17β-diol in mammalian tissues is catalysed by …
dehydroepi-androsterone and 5-androstene-3β,17β-diol in mammalian tissues is catalysed by …
The effect of oral contraceptive treatment on the serum concentration of dehydroisoandrosterone sulfate
JD Madden, L Milewich, CR Parker Jr, BR Carr…�- American journal of�…, 1978 - Elsevier
… employing procedures described by Milewich and associates8 and by Gomez-Sanchez and
associates9 The data were analyzed … L.: Twenty-four hour Dattem of the episodic secretion …
associates9 The data were analyzed … L.: Twenty-four hour Dattem of the episodic secretion …
Estrogen 16α-hydroxylase activity in human fetal tissues
L MILEWICH, PC MACDONALD…�- The Journal of Clinical�…, 1986 - academic.oup.com
Estrogen 16α-hydroxylase activity was measured in microsomes prepared from fetal tissues
of first and second trimester human abortuses using [16α- (3) H]estrone sulfate as substrate …
of first and second trimester human abortuses using [16α- (3) H]estrone sulfate as substrate …
Androstenedione metabolism by human lymphocytes
L Milewich, MG Whisenant, MK Sawyer�- Journal of Steroid Biochemistry, 1982 - Elsevier
… ascertained by the formation of androsterone (0.6 pmol/lx 10’ lymphocytes x 4 h); and 3/l-hydroxysteroid
oxidoreductase as evidenced by the formation of isoandrosterone (0.6 pmol/lx …
oxidoreductase as evidenced by the formation of isoandrosterone (0.6 pmol/lx …
Deoxycorticosterone biosynthesis in human kidney: potential for formation of a potent mineralocorticosteroid in its site of action.
CA Winkel, ER Simpson, L Milewich…�- Proceedings of the�…, 1980 - National Acad Sciences
The extra-adrenal formation of deoxycorticosterone (DOC) from plasma progesterone has
been demonstrated in humans. In those studies it was shown that in some persons the volume …
been demonstrated in humans. In those studies it was shown that in some persons the volume …
Adenylate cyclase from term human placenta and its regulation
L Milewich, TS Hendricks, JE Graham, NF Gant…�- Placenta, 1982 - Elsevier
The activation of placental AC by either Mg 2+ or Mn 2+ , in the presence and absence of NaF,
followed sigmoidal saturation kinetics. Mn 2+ enhanced maximally the NaF-stimulated Mg …
followed sigmoidal saturation kinetics. Mn 2+ enhanced maximally the NaF-stimulated Mg …
Ascorbic acid inhibition of aromatase activity in human placental tissue
L Milewich, GT Chen, PC MacDonald…�- Journal of Steroid�…, 1981 - Elsevier
… The marked inhibition of aromatase activity by high concentration l of ascorbic acid (Type
II inhibition) appeared to be related to these pH changes. We propose that the mechanism of …
II inhibition) appeared to be related to these pH changes. We propose that the mechanism of …