Mutational landscape of aggressive prostate tumors in African American men
KJ Lindquist, PL Paris, TJ Hoffmann, NJ Cardin…�- Cancer research, 2016 - AACR
Prostate cancer is the most frequently diagnosed and second most fatal nonskin cancer
among men in the United States. African American men are two times more likely to develop�…
among men in the United States. African American men are two times more likely to develop�…
Chromosome 17q12 variants contribute to risk of early-onset prostate cancer
In a recent genome-wide association study by Gudmundsson and colleagues, two prostate
cancer susceptibility loci were identified on chromosome 17q. The first locus, at 17q12, was�…
cancer susceptibility loci were identified on chromosome 17q. The first locus, at 17q12, was�…
A genome-wide association and admixture mapping study of bronchodilator drug response in African Americans with asthma
ML Spear, D Hu, M Pino-Yanes, S Huntsman…�- The�…, 2019 - nature.com
Short-acting β2-adrenergic receptor agonists (SABAs) are the most commonly prescribed
asthma medications worldwide. Response to SABAs is measured as bronchodilator drug�…
asthma medications worldwide. Response to SABAs is measured as bronchodilator drug�…
Dog introduction alters the home dust microbiota
Research has largely reported that dog exposure is associated with reduced allergic
disease risk. Responsible mechanism (s) are not understood. The goal was to investigate�…
disease risk. Responsible mechanism (s) are not understood. The goal was to investigate�…
[HTML][HTML] Current treatment of bilateral retinoblastoma: the impact of intraarterial and intravitreous chemotherapy
JH Francis, N Roosipu, AM Levin, SE Brodie, IJ Dunkel…�- Neoplasia, 2018 - Elsevier
PURPOSE: To evaluate the management and outcomes of na�ve bilateral retinoblastoma
treated at a single-center over a 5-year period during the era of ophthalmic artery�…
treated at a single-center over a 5-year period during the era of ophthalmic artery�…
Expression quantitative trait locus fine mapping of the 17q12–21 asthma locus in African American children: a genetic association and gene expression study
C Ober, CG McKennan, KM Magnaye…�- The Lancet�…, 2020 - thelancet.com
Background African ancestry is associated with a higher prevalence and greater severity of
asthma than European ancestries, yet genetic studies of the most common locus associated�…
asthma than European ancestries, yet genetic studies of the most common locus associated�…
Results from a prostate cancer admixture mapping study in African-American men
CH Bock, AG Schwartz, JJ Ruterbusch, AM Levin…�- Human genetics, 2009 - Springer
There are considerable racial disparities in prostate cancer risk, with a 60% higher
incidence rate among African-American (AA) men compared with European-American (EA)�…
incidence rate among African-American (AA) men compared with European-American (EA)�…
Deletion of flbA Results in Increased Secretome Complexity and Reduced Secretion Heterogeneity in Colonies of Aspergillus niger
P Krijgsheld, BM Nitsche, H Post…�- Journal of proteome�…, 2013 - ACS Publications
Aspergillus niger is a cell factory for the production of enzymes. This fungus secretes
proteins in the central part and at the periphery of the colony. The sporulating zone of the�…
proteins in the central part and at the periphery of the colony. The sporulating zone of the�…
[HTML][HTML] Admixture Fine-Mapping in African Americans Implicates XAF1 as a Possible Sarcoidosis Risk Gene
AM Levin, MC Iannuzzi, CG Montgomery, S Trudeau…�- PloS one, 2014 - journals.plos.org
Sarcoidosis is a complex, multi-organ granulomatous disease with a likely genetic
component. West African ancestry confers a higher risk for sarcoidosis than European�…
component. West African ancestry confers a higher risk for sarcoidosis than European�…
Breast milk transforming growth factor β is associated with neonatal gut microbial composition
AR Sitarik, KR Bobbitt, SL Havstad…�- Journal of pediatric�…, 2017 - journals.lww.com
Methods: A total of 52 maternal-child pairs were drawn from a racially diverse birth cohort
based in Detroit, Michigan. Breast milk and neonatal stool specimens were collected at 1�…
based in Detroit, Michigan. Breast milk and neonatal stool specimens were collected at 1�…