Autistic traits in epilepsy models: Why, when and how?
J Vel�škov�, JL Silverman, M Benson…�- Epilepsy research, 2018 - Elsevier
Autism spectrum disorder (ASD) is a common comorbidity of epilepsy and seizures and/or
epileptiform activity are observed in a significant proportion of ASD patients. Current�…
epileptiform activity are observed in a significant proportion of ASD patients. Current�…
Properties of place cell firing after damage to the visual cortex
V Paz‐Villagr�n, PP Lenck‐Santini…�- European Journal of�…, 2002 - Wiley Online Library
Hippocampal place cells were recorded while rats with lesions of the striate visual cortex
foraged for food pellets in a cylindrical arena. Compared to control rats, rats with striate�…
foraged for food pellets in a cylindrical arena. Compared to control rats, rats with striate�…
Cognitive and Behavioral Comorbidities in Epilepsy: The Treacherous Nature of Animal Models: TLE Models and Comorbidities
PP Lenck-Santini�- Epilepsy Currents, 2013 - journals.sagepub.com
TLE Models and Comorbidities and thereby constituted a valid model of TLE showed mild to
no spatial performance impairment. Recently, the same group used identical protocols (PILO�…
no spatial performance impairment. Recently, the same group used identical protocols (PILO�…
Postictal single‐cell firing patterns in the hippocampus
JL Zhou, PP Lenck‐Santini, GL Holmes�- Epilepsia, 2007 - Wiley Online Library
Purpose: Patients with epilepsy have varying degrees of postictal impairment including
confusion and amnesia. This impairment adds substantially to the disease burden of�…
confusion and amnesia. This impairment adds substantially to the disease burden of�…
Seizure-Induced Newborn Neurons Might Not be So Bad after All: Seizure-Induced Newborn Neurons
PP Lenck-Santini�- Epilepsy Currents, 2013 - journals.sagepub.com
To increase the normal rate of adult neurogenesis, the authors used the amygdala kindling
model of TLE, where electrical stimulations (99 stimulation sessions at a regimen of 3 per�…
model of TLE, where electrical stimulations (99 stimulation sessions at a regimen of 3 per�…
Temporal coordination: A key to understand cognitive and behavioral deficits in epilepsy
PP Lenck-Santini…�- Neurobiology of the�…, 2022 - books.google.com
The Clave, is an asymmetric rhythmic pattern that constitutes the core of the rhythmic
organization of Afro-Cuban music such as Son Cubano, Salsa, Mambo, Rumba, or Afro�…
organization of Afro-Cuban music such as Son Cubano, Salsa, Mambo, Rumba, or Afro�…
A test of the time estimation hypothesis of place cell goal-related activity
V Hok, PP Lenck-Santini, E Save…�- Journal of integrative�…, 2007 - World Scientific
Place cells are hippocampal pyramidal neurons that discharge strongly in relation to the rat's
location in the environment. We recently reported that many place cells recorded from rats�…
location in the environment. We recently reported that many place cells recorded from rats�…
Neuroaminidase reduces interictal spikes in a rat temporal lobe epilepsy model
Interictal spikes have been implicated in epileptogenesis and cognitive dysfunction in
epilepsy. Unfortunately, antiepileptic drugs have shown poor efficacy in suppressing�…
epilepsy. Unfortunately, antiepileptic drugs have shown poor efficacy in suppressing�…
[HTML][HTML] Status Epilepticus Induced Spontaneous Dentate Gyrus Spikes: In Vivo Current Source Density Analysis
SP Flynn, S Barrier, RC Scott, PP Lenck-Santini…�- PLoS�…, 2015 - journals.plos.org
The dentate gyrus is considered to function as an inhibitory gate limiting excitatory input to
the hippocampus. Following status epilepticus (SE), this gating function is reduced and�…
the hippocampus. Following status epilepticus (SE), this gating function is reduced and�…
Cognitive and behavioral comorbidities of epilepsy
Major comorbidities of epilepsy include cognitive impairment and behavioral dysfunction.
The type and degree of these comorbidities is dependent upon etiology, age�…
The type and degree of these comorbidities is dependent upon etiology, age�…