Chemogenetic techniques, such as designer receptors exclusively activated by designer
drugs (DREADDs), enable transient, reversible, and minimally invasive manipulation of�…

Natural hypersaline waters are widely distributed around the globe, as both continental
surface waters and sea floor lakes, the latter being maintained by the large density�…

Spatial and nonspatial auditory processing is hypothesized to occur in parallel dorsal and
ventral pathways, respectively. In this study, we tested the spatial and nonspatial sensitivity�…

The brain is a highly organized, dynamic system whose network architecture is often
assessed through resting functional magnetic resonance imaging (fMRI) functional�…

Measures of fMRI resting-state functional connectivity (rs-FC) are an essential tool for basic
and clinical investigations of fronto-limbic circuits. Understanding the relationship between�…

During normal vision, our eyes provide the brain with a continuous stream of useful
information about the world. How visually specialized areas of the cortex, such as face�…

Glucocorticoids remain a mainstay of modern medicine due to their ability to broadly
suppress immune activation. However, they cause severe adverse effects that warrant�…

Modulation of CD8 coreceptor levels can profoundly affect T-cell sensitivity to antigen. Here
we show that the heritable downregulation of CD8 during type 2 polarization of murine�…

The neural correlates that relate auditory categorization to aspects of goal-directed behavior,
such as decision-making, are not well understood. Since the prefrontal cortex plays an�…

Objectives Systemic lupus erythematosus (SLE) is a serious multisystem autoimmune
disease, mediated by disrupted B cell quiescence and typically treated with glucocorticoids�…