Chronic activation of NPFFR2 stimulates the stress-related depressive behaviors through HPA axis modulation

YT Lin, TY Liu, CY Yang, YL Yu, TC Chen…�- …, 2016 - Elsevier
Neuropeptide FF (NPFF) is a morphine-modulating peptide that regulates the analgesic
effect of opioids, and also controls food consumption and cardiovascular function through its�…

Activation of NPFFR2 leads to hyperalgesia through the spinal inflammatory mediator CGRP in mice

YT Lin, HL Liu, YJ Day, CC Chang, PH Hsu…�- Experimental�…, 2017 - Elsevier
Neuropeptide FF (NPFF) is recognized as an opioid modulating peptide that regulates
morphine-induced analgesia. The aim of this study was to delineate the role of NPFFR2 in�…

Importance of PLC-dependent PI3K/AKT and AMPK signaling in RANTES/CCR5 mediated macrophage chemotaxis

HC Chien, PC Chan, CC Tu, YJ Day…�- Infection and Drug�…, 2018 - ir.cnu.edu.tw
Regulated upon activation, normal T cell expressed, and secreted (RANTES), also known as
chemokine ligand 5 (CCL5), has been reported to facilitate macrophage migration, which�…

[HTML][HTML] Hydroxyethyl starch interferes with human blood ex vivo coagulation, platelet function and sedimentation

FC Liu, CH Liao, YW Chang, JT Liou, YJ Day�- Acta Anaesthesiologica�…, 2009 - Elsevier
BACKGROUND: Hydroxyethyl starch (HES) solutions are widely used for intravascular
volume expansion. In Taiwan, the medium molecular weight of HES 200/0.5 and HES�…

[HTML][HTML] Spatial and temporal analysis of nociception-related spinal cord matrix metalloproteinase expression in a murine neuropathic pain model

JT Liou, DCW Sum, FC Liu, CC Mao, YS Lai…�- Journal of the Chinese�…, 2013 - Elsevier
BACKGROUND: Although the mammalian central nervous system contains numerous matrix
metalloproteinases (MMPs), the significance of each MMP relative to nociception remains�…

The anti-aggregation effects of ondansetron on platelets involve IP3 signaling and MAP kinase pathway, but not 5-HT3-dependent pathway

FC Liu, JT Liou, HR Liao, CC Mao, P Yang, YJ Day�- Thrombosis Research, 2012 - Elsevier
Ondansetron is a 5-HT3 receptor antagonist with potent antiemetic, analgesic, and
antiphlogistic effects. Literature concerning 5-HT3 antagonists on platelets is limited. In this�…

tPA‐MMP‐9 axis plays a pivotal role in mobilization of endothelial progenitor cells from bone marrow to circulation and ischemic region for angiogenesis

S Leu, YJ Day, CK Sun, HK Yip�- Stem Cells International, 2016 - Wiley Online Library
We examined the role of tissue plasminogen activator‐(tPA‐) matrix metalloproteinase‐
(MMP‐) 9 in mobilizing endothelial progenitor cells (EPCs) from bone marrow to circulation�…

A new insight of anti-platelet effects of sirtinol in platelets aggregation via cyclic AMP phosphodiesterase

FC Liu, CH Liao, YW Chang, JT Liou, YJ Day�- Biochemical pharmacology, 2009 - Elsevier
Sirtinol, a cell permeable six-membered lactone ring, is derived from naphthol and potent
inhibitor of SIR2 and its naphtholic may have the inhibitory effects on platelets aggregation�…

[HTML][HTML] Comparison of the effects of atropine and labetalol on trigeminocardiac reflex-induced hemodynamic alterations during percutaneous microballoon�…

CY Chen, CF Luo, YC Hsu, JF Chen, YJ Day�- Acta Anaesthesiologica�…, 2012 - Elsevier
BACKGROUND: A significant abrupt drop in heart rate is the most frequent complication
during percutaneous microballoon compression of the trigeminal ganglion. It is suggested�…

Sirtinol attenuates hepatic injury and pro‐inflammatory cytokine production following trauma‐hemorrhage in male Sprague–Dawley rats

FC LIU, YJ DAY, JT LIOU, YT LAU…�- Acta anaesthesiologica�…, 2008 - Wiley Online Library
Background: Although studies have demonstrated that sirtinol administration following
adverse circulatory conditions is known to be protective, the mechanism by which sirtinol�…