Activation of the adenosine A2A receptor (A2AR) at the time of reperfusion has been shown
to reduce ischemia–reperfusion injury in peripheral tissues and spinal cord. In this study we�…

Neurological complications contribute largely to the morbidity and mortality in patients with
acute renal failure. In order to study pathophysiological complications of renal failure, a�…

CD103 is a marker for identification of effector/memory regulatory T cells (Tregs). CD103+
Tregs are potent suppressors of tissue inflammation in several infectious diseases�…

Background: This study tested the hypothesis that preactivated and disaggregated shape-
changed platelet (PreD-SCP) therapy attenuates lung injury from acute respiratory distress�…

Chemokine (C–C motif) ligand 5 (CCL5) and CCR5, one of its receptors have been reported
to be highly expressed in white adipose tissue (WAT) and are associated with the�…

Acetaminophen (APAP) overdose results in the production of reactive oxygen species
(ROS), hepatocyte necrosis, and cell death, and leads to acute liver failure. Interleukin-17 (IL�…

P-selectin is required for neutrophils and macrophage infiltration into injured site and
contributes to generation of behavioral hypersensitivity in a murine model of neuropathic�…

Object Due to the usefulness of mouse genetics, there is a need to improve procedures for
producing and assessing spinal cord injury (SCI) in mice. The authors describe an improved�…

Background The functions of free radicals on the effects of insulin that result in protection
against cerebral ischemic insult in diabetes remain undefined. This present study aims to�…

KATP channels play an important role in physiology and pathophysiology of many tissues.
As in the pancreatic beta cells, they couple the change of blood glucose with insulin release�…