Structure, function, and pharmacology of glutamate receptor ion channels
Many physiologic effects of l-glutamate, the major excitatory neurotransmitter in the
mammalian central nervous system, are mediated via signaling by ionotropic glutamate�…
mammalian central nervous system, are mediated via signaling by ionotropic glutamate�…
[HTML][HTML] The molecular and systems biology of memory
ER Kandel, Y Dudai, MR Mayford�- Cell, 2014 - cell.com
Learning and memory are two of the most magical capabilities of our mind. Learning is the
biological process of acquiring new knowledge about the world, and memory is the process�…
biological process of acquiring new knowledge about the world, and memory is the process�…
[HTML][HTML] The Tolman-Eichenbaum machine: unifying space and relational memory through generalization in the hippocampal formation
The hippocampal-entorhinal system is important for spatial and relational memory tasks. We
formally link these domains, provide a mechanistic understanding of the hippocampal role in�…
formally link these domains, provide a mechanistic understanding of the hippocampal role in�…
Microstructure of a spatial map in the entorhinal cortex
The ability to find one's way depends on neural algorithms that integrate information about
place, distance and direction, but the implementation of these operations in cortical�…
place, distance and direction, but the implementation of these operations in cortical�…
Pattern separation in the hippocampus
The ability to discriminate among similar experiences is a crucial feature of episodic
memory. This ability has long been hypothesized to require the hippocampus, and�…
memory. This ability has long been hypothesized to require the hippocampus, and�…
Dentate gyrus circuits for encoding, retrieval and discrimination of episodic memories
T Hainmueller, M Bartos�- Nature Reviews Neuroscience, 2020 - nature.com
The dentate gyrus (DG) has a key role in hippocampal memory formation. Intriguingly, DG
lesions impair many, but not all, hippocampus-dependent mnemonic functions, indicating�…
lesions impair many, but not all, hippocampus-dependent mnemonic functions, indicating�…
What learning systems do intelligent agents need? Complementary learning systems theory updated
D Kumaran, D Hassabis, JL McClelland�- Trends in cognitive sciences, 2016 - cell.com
We update complementary learning systems (CLS) theory, which holds that intelligent
agents must possess two learning systems, instantiated in mammalians in neocortex and�…
agents must possess two learning systems, instantiated in mammalians in neocortex and�…
Place cells, grid cells, and the brain's spatial representation system
EI Moser, E Kropff, MB Moser�- Annu. Rev. Neurosci., 2008 - annualreviews.org
More than three decades of research have demonstrated a role for hippocampal place cells
in representation of the spatial environment in the brain. New studies have shown that place�…
in representation of the spatial environment in the brain. New studies have shown that place�…
[HTML][HTML] Mouse Cre-LoxP system: general principles to determine tissue-specific roles of target genes
Genetically engineered mouse models are commonly preferred for studying the human
disease due to genetic and pathophysiological similarities between mice and humans. In�…
disease due to genetic and pathophysiological similarities between mice and humans. In�…
[HTML][HTML] Bridging animal and human models of exercise-induced brain plasticity
Significant progress has been made in understanding the neurobiological mechanisms
through which exercise protects and restores the brain. In this feature review, we integrate�…
through which exercise protects and restores the brain. In this feature review, we integrate�…