Diabetic nephropathy—emerging epigenetic mechanisms

M Kato, R Natarajan�- Nature Reviews Nephrology, 2014 - nature.com
Diabetic nephropathy (DN), a severe microvascular complication frequently associated with
both type 1 and type 2 diabetes mellitus, is a leading cause of renal failure. The condition�…

Epigenetic regulations in diabetic nephropathy

Z Lu, N Liu, F Wang�- Journal of diabetes research, 2017 - Wiley Online Library
Diabetic nephropathy (DN) is a chronic complication of diabetes and the most common
cause of end‐stage kidney disease. It has been reported that multiple factors are involved in�…

The pathogenesis of diabetic nephropathy

S Dronavalli, I Duka, GL Bakris�- Nature clinical practice Endocrinology�…, 2008 - nature.com
Abstract Between 20% and 40% of patients with diabetes ultimately develop diabetic
nephropathy, which in the US is the most common cause of end-stage renal disease�…

Transcription factors in the pathogenesis of diabetic nephropathy

AP Sanchez, K Sharma�- Expert reviews in molecular medicine, 2009 - cambridge.org
Approximately a third of patients with diabetes develop diabetic kidney disease, and
diabetes is the leading cause of end-stage renal disease in most developed countries�…

[HTML][HTML] Epigenetics in the pathogenesis of diabetic nephropathy: Epigenetics in the pathogenesis of diabetic nephropathy

X Li, L Lu, W Hou, T Huang, X Chen, J Qi…�- Acta Biochimica et�…, 2022 - ncbi.nlm.nih.gov
Diabetic nephropathy (DN), which is a common microvascular complication with a high
incidence in diabetic patients, greatly increases the mortality of patients. With further study�…

Epigenetic modifications in the pathogenesis of diabetic nephropathy

MA Reddy, JT Park, R Natarajan�- Seminars in nephrology, 2013 - Elsevier
Diabetic nephropathy (DN) is a leading cause of end-stage renal disease. Diabetic vascular
complications such as DN can progress despite subsequent glycemic control, suggesting a�…

[HTML][HTML] Recent advances in diabetic kidney diseases: from kidney injury to kidney fibrosis

PH Hung, YC Hsu, TH Chen, CL Lin�- International Journal of Molecular�…, 2021 - mdpi.com
Diabetic kidney disease (DKD) is the leading cause of chronic kidney disease and end-
stage renal disease. The natural history of DKD includes glomerular hyperfiltration�…

[HTML][HTML] Epigenetics and inflammation in diabetic nephropathy

BY Shao, SF Zhang, HD Li, XM Meng…�- Frontiers in�…, 2021 - frontiersin.org
Diabetic nephropathy (DN) leads to high morbidity and disability. Inflammation plays a
critical role in the pathogenesis of DN, which involves renal cells and immune cells, the�…

Epigenetics in diabetic kidney disease

MA Reddy, R Natarajan�- Journal of the American Society of�…, 2011 - journals.lww.com
Regulated gene expression by transcription factor networks is critical for normal kidney
function. Disruption of these complex networks leads to biochemical aberrations associated�…

Diabetic nephropathy: the regulatory interplay between epigenetics and microRNAs

H Sankrityayan, YA Kulkarni, AB Gaikwad�- Pharmacological research, 2019 - Elsevier
Diabetic nephropathy (DN) is still one of the leading causes of end-stage renal disease
despite the emergence of different therapies to counter the metabolic, hemodynamic and�…