Cytochrome P-450s as toxicogenic catalysts: the influence of dehydroepiandrosterone.

RW Estabrook, L Milewich…�- Princess Takamatsu�…, 1990 - europepmc.org
The cytochrome P-450s catalyze the oxidative transformation of a large number of endogenous
and exogenous chemicals in plants, insects, and mammals. One consequence of this …

The 3β-hydroxysteroid dehydrogenase gene family of enzymes

JI Mason�- Trends in Endocrinology & Metabolism, 1993 - cell.com
It now is apparent that a family of closely related genes encode for 38 hydroxysteroid
dehydrogenase (3BHSD). Studies on the regulation of these genes are in their infancy, but the …

[PDF][PDF] Hyperandrogenic states in pregnancy

N Kanova, M Bicikova�- Physiological Research, 2011 - biomed.cas.cz
… ) is the main precursor of the synthesis of steroid hormones in the placenta, which is why
the plasmatic level of both of these androgens drops by nearly half during pregnancy (Milewich

[HTML][HTML] Estrogens, Obesity, Inflammation, and Breast Cancer—What Is the Link?

KA Brown, ER Simpson�- Seminars in Reproductive Medicine, 2015 - thieme-connect.com
It gives me great pleasure to contribute to this special issue of Seminars which honors the
career of Bruce Carr. As it happens, Bruce was my first Fellow upon my arrival at the Green …

Intracrinology

F Labrie�- Molecular and cellular endocrinology, 1991 - Elsevier
… Despite the early description of circulating DHEA-S in the circulation (Bautieu, l%Ot and the
fact that its circulating concentration in adult men and women is higher than any other steroid …

Cross-contamination of cells in culture

WA Nelson-Rees, DW Daniels, RR Flandermeyer�- Science, 1981 - science.org
Lists are presented of references to all known publications describing cell properties that
serve to characterize (i) known strains of HeLa and purported human cell lines indicted as …

Estrogen production by fetal rat gonads

JP Weniger�- The Journal of steroid biochemistry and molecular�…, 1993 - Elsevier
… However, there was renewed interest in 1977, when Milewich et al. [10] using tritiated testosterone
… Recherches sur l'intersexualit6 exp6rimentale produite par la m6thode des greffes de …

Major enzymes controlling the androgenic pressure in the developing lung

Y Tremblay, PR Provost�- The Journal of steroid biochemistry and�…, 2013 - Elsevier
… Following the pioneering work of Milewich et al. showing the capability of the human lung
to … Combined with the work of Milewich et al., the first two reports of this new era of research …

[PDF][PDF] Reduced progesterone metabolites in human late pregnancy

M Hill, A Parizek, R Kancheva, JE Jirasek�- Physiological Research, 2011 - biomed.cas.cz
In this review, we focused on the intersection between steroid metabolomics, obstetrics and
steroid neurophysiology to give a comprehensive insight into the role of sex hormones and …

Sexual differentiation: early hormone synthesis and action

JD Wilson, JE Griffin, FW George�- Biology of reproduction, 1980 - academic.oup.com
Male and female embryos develop in an identical fashion during the initial phases of gestation
and it is only after the gonads differentiate and endocrine function of the testis is initiated …