Articles with public access mandates - Kiran Sapkota, Ph.D.Learn more
Not available anywhere: 1
Pharmacological characterization of a novel negative allosteric modulator of NMDA receptors, UBP792
K Sapkota, ES Burnell, MW Irvine, G Fang, DY Gawande, SM Dravid, ...
Neuropharmacology 201, 108818, 2021
Mandates: US National Institutes of Health, UK Biotechnology and Biological Sciences�…
Available somewhere: 14
The origin of NMDA receptor hypofunction in schizophrenia
K Nakazawa, K Sapkota
Pharmacology & therapeutics 205, 107426, 2020
Mandates: US National Institutes of Health
GluN2D N-methyl-d-aspartate receptor subunit contribution to the stimulation of brain activity and gamma oscillations by ketamine: implications for schizophrenia
K Sapkota, Z Mao, P Synowicki, D Lieber, M Liu, T Ikezu, V Gautam, ...
Journal of Pharmacology and Experimental Therapeutics 356 (3), 702-711, 2016
Mandates: US National Institutes of Health
Positive and Negative Allosteric Modulators of N-Methyl-d-aspartate (NMDA) Receptors: Structure–Activity Relationships and Mechanisms of Action
ES Burnell, M Irvine, G Fang, K Sapkota, DE Jane, DT Monaghan
Journal of medicinal chemistry 62 (1), 3-23, 2018
Mandates: US National Institutes of Health, UK Biotechnology and Biological Sciences�…
GSK3β inhibition restores cortical gamma oscillation and cognitive behavior in a mouse model of NMDA receptor hypofunction relevant to schizophrenia
K Nakao, M Singh, K Sapkota, BC Hagler, RN Hunter, C Raman, ...
Neuropsychopharmacology 45 (13), 2207-2218, 2020
Mandates: US National Institutes of Health
Structural basis of subtype-selective competitive antagonism for GluN2C/2D-containing NMDA receptors
JX Wang, MW Irvine, ES Burnell, K Sapkota, RJ Thatcher, M Li, ...
Nature communications 11 (1), 423, 2020
Mandates: US Department of Energy, US National Institutes of Health, UK Biotechnology�…
The NMDA receptor intracellular C-terminal domains reciprocally interact with allosteric modulators
K Sapkota, K Dore, K Tang, M Irvine, G Fang, ES Burnell, R Malinow, ...
Biochemical pharmacology 159, 140-153, 2019
Mandates: US National Institutes of Health, UK Biotechnology and Biological Sciences�…
Pananx notoginseng saponins attenuate CCL2-induced cognitive deficits in rats via anti-inflammation and anti-apoptosis effects that involve suppressing over-activation of NMDA�…
Y Zhou, J Chen, K Sapkota, J Long, Y Liao, J Jiang, B Liang, J Wei, ...
Biomedicine & Pharmacotherapy 127, 110139, 2020
Mandates: National Natural Science Foundation of China
Mechanism and properties of positive allosteric modulation of N-methyl-d-aspartate receptors by 6-alkyl 2-naphthoic acid derivatives
K Sapkota, MW Irvine, G Fang, ES Burnell, N Bannister, A Volianskis, ...
Neuropharmacology 125, 64-79, 2017
Mandates: US National Institutes of Health, UK Biotechnology and Biological Sciences�…
Differential regulation of STP, LTP and LTD by structurally diverse NMDA receptor subunit-specific positive allosteric modulators
G France, R Volianskis, R Ingram, N Bannister, R Roth�rmel, MW Irvine, ...
Neuropharmacology 202, 108840, 2022
Mandates: US National Institutes of Health, Canadian Institutes of Health Research, UK�…
Investigation of the structural requirements for N-methyl-D-aspartate receptor positive and negative allosteric modulators based on 2-naphthoic acid
MW Irvine, G Fang, K Sapkota, ES Burnell, A Volianskis, BM Costa, ...
European journal of medicinal chemistry 164, 471-498, 2019
Mandates: US National Institutes of Health, UK Biotechnology and Biological Sciences�…
A single-channel mechanism for pharmacological potentiation of GluN1/GluN2A NMDA receptors
DA Chopra, K Sapkota, MW Irvine, G Fang, DE Jane, DT Monaghan, ...
Scientific reports 7 (1), 6933, 2017
Mandates: US National Institutes of Health, UK Biotechnology and Biological Sciences�…
5-HT2A receptor dysregulation in a schizophrenia relevant mouse model of NMDA receptor hypofunction
K Nakao, M Singh, K Sapkota, A Fitzgerald, JJ Hablitz, K Nakazawa
Translational Psychiatry 12 (1), 168, 2022
Mandates: US National Institutes of Health
Maturation of GABAergic Synaptic Transmission From Neocortical Parvalbumin Interneurons Involves N-methyl-D-aspartate Receptor Recruitment of Cav2. 1 Channels
M Singh, K Sapkota, K Sakimura, M Kano, RM Cowell, ...
Neuroscience 513, 38-53, 2023
Mandates: US National Institutes of Health
Target validation and pharmacological characterization of novel NMDAR modulators.
K Sapkota
University of Nebraska Medical Center, Omaha, Nebraska, USA, 2016
Mandates: Department of Science & Technology, India
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