Dosing & Uses
AdultPediatric
Non-Small Cell Lung Cancer
Pending FDA approval for first-line treatment of metastatic ALK–positive non-small cell lung cancer
Safety and efficacy not established
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Pharmacology
Mechanism of Action
Anaplastic lymphoma kinase (ALK) inhibitor that binds to and inhibits ALK kinase, ALK fusion proteins, and ALK point mutation variants
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Images
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Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.
