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Page 1
Network-based elucidation of colon cancer drug resistance by phosphoproteomic time-series analysis.
Rosenberger G, Li W, Turunen M, He J, Subramaniam PS, Pampou S, Griffin AT, Karan C, Kerwin P, Murray D, Honig B, Liu Y, Califano A. Rosenberger G, et al. Among authors: califano a. bioRxiv [Preprint]. 2023 Feb 16:2023.02.15.528736. doi: 10.1101/2023.02.15.528736. bioRxiv. 2023. Update in: Nat Commun. 2024 May 9;15(1):3909. doi: 10.1038/s41467-024-47957-3. PMID: 36824919 Free PMC article. Updated. Preprint.
Elucidating Compound Mechanism of Action by Network Perturbation Analysis.
Woo JH, Shimoni Y, Yang WS, Subramaniam P, Iyer A, Nicoletti P, Rodríguez Martínez M, López G, Mattioli M, Realubit R, Karan C, Stockwell BR, Bansal M, Califano A. Woo JH, et al. Among authors: califano a. Cell. 2015 Jul 16;162(2):441-451. doi: 10.1016/j.cell.2015.05.056. Cell. 2015. PMID: 26186195 Free PMC article.
Systematic, network-based characterization of therapeutic target inhibitors.
Shen Y, Alvarez MJ, Bisikirska B, Lachmann A, Realubit R, Pampou S, Coku J, Karan C, Califano A. Shen Y, et al. Among authors: califano a. PLoS Comput Biol. 2017 Oct 12;13(10):e1005599. doi: 10.1371/journal.pcbi.1005599. eCollection 2017 Oct. PLoS Comput Biol. 2017. PMID: 29023443 Free PMC article.
A precision oncology approach to the pharmacological targeting of mechanistic dependencies in neuroendocrine tumors.
Alvarez MJ, Subramaniam PS, Tang LH, Grunn A, Aburi M, Rieckhof G, Komissarova EV, Hagan EA, Bodei L, Clemons PA, Dela Cruz FS, Dhall D, Diolaiti D, Fraker DA, Ghavami A, Kaemmerer D, Karan C, Kidd M, Kim KM, Kim HC, Kunju LP, Langel Ü, Li Z, Lee J, Li H, LiVolsi V, Pfragner R, Rainey AR, Realubit RB, Remotti H, Regberg J, Roses R, Rustgi A, Sepulveda AR, Serra S, Shi C, Yuan X, Barberis M, Bergamaschi R, Chinnaiyan AM, Detre T, Ezzat S, Frilling A, Hommann M, Jaeger D, Kim MK, Knudsen BS, Kung AL, Leahy E, Metz DC, Milsom JW, Park YS, Reidy-Lagunes D, Schreiber S, Washington K, Wiedenmann B, Modlin I, Califano A. Alvarez MJ, et al. Among authors: califano a. Nat Genet. 2018 Jul;50(7):979-989. doi: 10.1038/s41588-018-0138-4. Epub 2018 Jun 18. Nat Genet. 2018. PMID: 29915428 Free PMC article.
Oncoprotein-specific molecular interaction maps (SigMaps) for cancer network analyses.
Broyde J, Simpson DR, Murray D, Paull EO, Chu BW, Tagore S, Jones SJ, Griffin AT, Giorgi FM, Lachmann A, Jackson P, Sweet-Cordero EA, Honig B, Califano A. Broyde J, et al. Among authors: califano a. Nat Biotechnol. 2021 Feb;39(2):215-224. doi: 10.1038/s41587-020-0652-7. Epub 2020 Sep 14. Nat Biotechnol. 2021. PMID: 32929263 Free PMC article.
A model for network-based identification and pharmacological targeting of aberrant, replication-permissive transcriptional programs induced by viral infection.
Laise P, Stanifer ML, Bosker G, Sun X, Triana S, Doldan P, La Manna F, De Menna M, Realubit RB, Pampou S, Karan C, Alexandrov T, Kruithof-de Julio M, Califano A, Boulant S, Alvarez MJ. Laise P, et al. Among authors: califano a. Commun Biol. 2022 Jul 19;5(1):714. doi: 10.1038/s42003-022-03663-8. Commun Biol. 2022. PMID: 35854100 Free PMC article.
350 results