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A novel class of cardioprotective small-molecule PTP inhibitors.
Antonucci S, Di Sante M, Sileikyte J, Deveraux J, Bauer T, Bround MJ, Menabò R, Paillard M, Alanova P, Carraro M, Ovize M, Molkentin JD, Cohen M, Forte MA, Bernardi P, Di Lisa F, Murphy E. Antonucci S, et al. Among authors: bround mj. Pharmacol Res. 2020 Jan;151:104548. doi: 10.1016/j.phrs.2019.104548. Epub 2019 Nov 20. Pharmacol Res. 2020. PMID: 31759087 Free PMC article.
MCUb Induction Protects the Heart From Postischemic Remodeling.
Huo J, Lu S, Kwong JQ, Bround MJ, Grimes KM, Sargent MA, Brown ME, Davis ME, Bers DM, Molkentin JD. Huo J, et al. Among authors: bround mj. Circ Res. 2020 Jul 17;127(3):379-390. doi: 10.1161/CIRCRESAHA.119.316369. Epub 2020 Apr 17. Circ Res. 2020. PMID: 32299299 Free PMC article.
Cardiac Ryanodine Receptor (Ryr2)-mediated Calcium Signals Specifically Promote Glucose Oxidation via Pyruvate Dehydrogenase.
Bround MJ, Wambolt R, Cen H, Asghari P, Albu RF, Han J, McAfee D, Pourrier M, Scott NE, Bohunek L, Kulpa JE, Chen SR, Fedida D, Brownsey RW, Borchers CH, Foster LJ, Mayor T, Moore ED, Allard MF, Johnson JD. Bround MJ, et al. J Biol Chem. 2016 Nov 4;291(45):23490-23505. doi: 10.1074/jbc.M116.756973. Epub 2016 Sep 12. J Biol Chem. 2016. PMID: 27621312 Free PMC article.
Cardiac ryanodine receptors control heart rate and rhythmicity in adult mice.
Bround MJ, Asghari P, Wambolt RB, Bohunek L, Smits C, Philit M, Kieffer TJ, Lakatta EG, Boheler KR, Moore ED, Allard MF, Johnson JD. Bround MJ, et al. Cardiovasc Res. 2012 Dec 1;96(3):372-80. doi: 10.1093/cvr/cvs260. Epub 2012 Aug 6. Cardiovasc Res. 2012. PMID: 22869620 Free PMC article.
16 results