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Clinical experience with moroctocog alfa (AF-CC) in younger paediatric patients with severe haemophilia A: Two open-label studies.
Rusen L , Kavakli K, Korth-Bradley J, Huard F, Rendo P, Fuiman J, Baumann JA, Smith L, Alvey C, Rupon J.
Rusen L , et al.
Haemophilia. 2018 Jul;24(4):604-610. doi: 10.1111/hae.13466. Epub 2018 Mar 26.
Haemophilia. 2018.
PMID: 29582525
Clinical Trial.
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Prospective surveillance study of haemophilia A patients switching from moroctocog alfa or other factor VIII products to moroctocog alfa albumin-free cell culture (AF-CC) in usual care settings.
Parra Lopez R, Nemes L, Jimenez-Yuste V, Rusen L , Cid AR, Charnigo RJ, Baumann JA, Smith L, Korth-Bradley JM, Rendo P.
Parra Lopez R, et al. Among authors: rusen l .
Thromb Haemost. 2015 Oct;114(4):676-84. doi: 10.1160/TH14-09-0760. Epub 2015 Aug 13.
Thromb Haemost. 2015.
PMID: 26293201
Clinical Trial.
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Pharmacokinetics, efficacy and safety of BAX326, a novel recombinant factor IX: a prospective, controlled, multicentre phase I/III study in previously treated patients with severe (FIX level <1%) or moderately severe (FIX level ≤2%) haemophilia B.
Windyga J, Lissitchkov T, Stasyshyn O, Mamonov V, Rusen L , Lamas JL, Oh MS, Chapman M, Fritsch S, Pavlova BG, Wong WY, Abbuehl BE.
Windyga J, et al. Among authors: rusen l .
Haemophilia. 2014 Jan;20(1):15-24. doi: 10.1111/hae.12228. Epub 2013 Jul 9.
Haemophilia. 2014.
PMID: 23834666
Clinical Trial.
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Recombinant factor IX (BAX326) in previously treated paediatric patients with haemophilia B: a prospective clinical trial.
Urasinski T, Stasyshyn O, Andreeva T, Rusen L , Perina FG, Oh MS, Chapman M, Pavlova BG, Valenta-Singer B, Abbuehl BE.
Urasinski T, et al. Among authors: rusen l .
Haemophilia. 2015 Mar;21(2):196-203. doi: 10.1111/hae.12548. Epub 2014 Dec 11.
Haemophilia. 2015.
PMID: 25495591
Clinical Trial.
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Safe switching from a pdFIX (Immunine®) to a rFIX (Bax326).
Solano Trujillo MH, Stasyshyn O, Rusen L , Serban M, Lamas JL, Perina FG, Urasinski T, Oh M, Knowlton WB, Valenta-Singer B, Pavlova BG, Abbuehl B.
Solano Trujillo MH, et al. Among authors: rusen l .
Haemophilia. 2014 Sep;20(5):674-81. doi: 10.1111/hae.12444. Epub 2014 Apr 10.
Haemophilia. 2014.
PMID: 24720694
Clinical Trial.
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PK-guided personalized prophylaxis with Nuwiq® (human-cl rhFVIII) in adults with severe haemophilia A.
Lissitchkov T, Rusen L , Georgiev P, Windyga J, Klamroth R, Gercheva L, Nemes L, Tiede A, Bichler J, Knaub S, Belyanskaya L, Walter O, Pasi KJ.
Lissitchkov T, et al. Among authors: rusen l .
Haemophilia. 2017 Sep;23(5):697-704. doi: 10.1111/hae.13251. Epub 2017 Apr 27.
Haemophilia. 2017.
PMID: 28452151
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BAY 81-8973 safety and efficacy for prophylaxis and treatment of bleeds in previously treated children with severe haemophilia A: results of the LEOPOLD Kids Trial.
Ljung R, Kenet G, Mancuso ME, Kaleva V, Rusen L , Tseneklidou-Stoeter D, Michaels LA, Shah A, Hong W, Maas Enriquez M; investigators of the LEOPOLD Kids Trial.
Ljung R, et al. Among authors: rusen l .
Haemophilia. 2016 May;22(3):354-60. doi: 10.1111/hae.12866. Epub 2015 Dec 9.
Haemophilia. 2016.
PMID: 26663410
Clinical Trial.
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Individual thrombin generation and spontaneous bleeding rate during personalized prophylaxis with Nuwiq® (human-cl rhFVIII) in previously treated patients with severe haemophilia A.
Dargaud Y, Negrier C, Rusen L , Windyga J, Georgiev P, Bichler J, Solomon C, Knaub S, Lissitchkov T, Klamroth R.
Dargaud Y, et al. Among authors: rusen l .
Haemophilia. 2018 Jul;24(4):619-627. doi: 10.1111/hae.13493. Epub 2018 May 31.
Haemophilia. 2018.
PMID: 29855112
Clinical Trial.
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