Review
doi: 10.1177/174182679600300402.
Oxidative hypothesis of atherogenesis
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- PMID: 8946263
- DOI: 10.1177/174182679600300402
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Review
Oxidative hypothesis of atherogenesis
J Cardiovasc Risk.
1996 Aug.
Abstract
The oxidative hypothesis of atherogenesis suggests that an important event in the development of atherosclerotic lesions is the oxidation of lipids contained in low-density lipoprotein (LDL). This hypothesis is supported by a number of in-vitro and in-vivo studies demonstrating the proatherogenic properties of oxidized LDL, the occurrence of oxidatively modified LDL in atherosclerotic lesions and the reduction of atherosclerotic events by antioxidants.
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