Influence of dietary cholesterol and fat on serum lipids in men
- PMID: 7310532
- DOI: 10.1093/jn/111.12.2069
Influence of dietary cholesterol and fat on serum lipids in men
Abstract
The effect of changes in dietary cholesterol and fat on serum lipids was studied in 32 healthy men (mean age = 24.8 years). Subjects were fed a controlled diet for 10 days providing 42 to 45% of the total calories from fat, a P/S ratio of 0.3 to 0.5 and two eggs per day. During the next eight weeks, 16 subjects received each of the following diets for four weeks in a crossover design: 1) a control diet with two eggs per day or 2) the control diet with eggs replaced by a cholesterol-free egg substitute. The remaining 16 subjects received each of the following diets in a similar crossover design: 1) a modified-fat diet containing 35% of the total calories from fat, a P/S ratio greater than or equal to 1.0 and two eggs per day or 2) the same modified-fat diet with the egg substitute replacing the eggs. The two-week cycle of menus repeated throughout the study included a wide variety of foods commonly consumed in this country. Although the response of individual subjects varied, analysis of variance showed a significant decrease in serum total cholesterol related to replacement of eggs with the egg substitute and to modification in the type and amount of dietary fat. A significant diet-treatment interaction or sequencing effect was not found. Change in cholesterol intake related to addition or deletion of two eggs in the daily diet had no significant effect on serum triglycerides, high density lipoprotein cholesterol, or relative lipoprotein concentrations.
Similar articles
-
Increases in dietary cholesterol and fat raise levels of apoprotein E-containing lipoproteins in the plasma of man.J Clin Endocrinol Metab. 1983 Jun;56(6):1108-15. doi: 10.1210/jcem-56-6-1108. J Clin Endocrinol Metab. 1983. PMID: 6841553
-
Effect of egg cholesterol and dietary fats on plasma lipids, lipoproteins, and apoproteins of normal women consuming natural diets.J Lipid Res. 1987 May;28(5):518-27. J Lipid Res. 1987. PMID: 3598397
-
A double-blind, randomized, controlled trial of the effects of two eggs per day in moderately hypercholesterolemic and combined hyperlipidemic subjects taught the NCEP step I diet.J Am Coll Nutr. 1997 Dec;16(6):551-61. J Am Coll Nutr. 1997. PMID: 9430083 Clinical Trial.
-
Reduction of low density and high density lipoprotein cholesterol by fat-modified diets. A survey of recent findings.Hum Nutr Clin Nutr. 1982;36(3):203-11. Hum Nutr Clin Nutr. 1982. PMID: 6749766 Review.
-
Dietary Cholesterol, Serum Lipids, and Heart Disease: Are Eggs Working for or Against You?Nutrients. 2018 Mar 29;10(4):426. doi: 10.3390/nu10040426. Nutrients. 2018. PMID: 29596318 Free PMC article. Review.
Cited by
-
Egg Consumption and Human Cardio-Metabolic Health in People with and without Diabetes.Nutrients. 2015 Sep 3;7(9):7399-420. doi: 10.3390/nu7095344. Nutrients. 2015. PMID: 26404366 Free PMC article. Review.
-
Dietary interventions (plant sterols, stanols, omega-3 fatty acids, soy protein and dietary fibers) for familial hypercholesterolaemia.Cochrane Database Syst Rev. 2014 Jun 10;2014(6):CD001918. doi: 10.1002/14651858.CD001918.pub3. Cochrane Database Syst Rev. 2014. PMID: 24913720 Free PMC article. Review.
-
Low-fat diets do not lower plasma cholesterol levels in healthy men compared to high-fat diets with similar fatty acid composition at constant caloric intake.Lipids. 1995 Nov;30(11):969-76. doi: 10.1007/BF02536280. Lipids. 1995. PMID: 8569436
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical