Downbeat nystagmus: a type of central vestibular nystagmus
- PMID: 6970904
- DOI: 10.1212/wnl.31.3.304
Downbeat nystagmus: a type of central vestibular nystagmus
Abstract
We used electrooculography to study horizontal and vertical eye movements in 17 patients with downbeat nystagmus (Chiari malformation, 9; multiple sclerosis, 2; olivopontocerebellar atrophy, 2; brainstem infarction, 2; and idiopathic nystagmus, 2). In all patients the velocity of slow components of the spontaneous nystagmus increased on lateral gaze, remained relatively unchanged with loss of fixation, and increased markedly after rapid positional changes in the sagittal plane. Horizontal and vertical smooth pursuit was impaired in all patients. Vertical pursuit recordings at multiple ramp velocities suggested superimposition of the spontaneous nystagmus on attempted pursuit rather than selective impairment of downward pursuit. Finally, all patients had impaired fixation suppression of vestibular nystagmus when they were rotated with a fixation point moving with their head. We conclude that downbeat nystagmus is a type of central vestibular nystagmus resulting from an imbalance in the central vertical vestibuloocular pathways.
Similar articles
-
[Update on central oculomotor disorders and nystagmus].Laryngorhinootologie. 2024 Jun;103(6):413-421. doi: 10.1055/a-2192-7319. Epub 2024 Jan 9. Laryngorhinootologie. 2024. PMID: 38195848 Review. German.
-
Central oculomotor disturbances and nystagmus: a window into the brainstem and cerebellum.Dtsch Arztebl Int. 2011 Mar;108(12):197-204. doi: 10.3238/arztebl.2011.0197. Epub 2011 Mar 25. Dtsch Arztebl Int. 2011. PMID: 21505601 Free PMC article. Review.
-
Three-dimensional eye position and slow phase velocity in humans with downbeat nystagmus.J Neurophysiol. 2003 Jan;89(1):338-54. doi: 10.1152/jn.00297.2002. J Neurophysiol. 2003. PMID: 12522184
-
Torsional nystagmus during vertical pursuit.J Neuroophthalmol. 1996 Jun;16(2):79-90. J Neuroophthalmol. 1996. PMID: 8797162
-
Analysis of downbeat nystagmus. Otolithic vs semicircular canal influences.Arch Neurol. 1986 Jan;43(1):52-5. doi: 10.1001/archneur.1986.00520010048021. Arch Neurol. 1986. PMID: 3484626
Cited by
-
Paraneoplastic Syndrome Case Presented As Nystagmus and Ataxia.Cureus. 2024 Feb 28;16(2):e55153. doi: 10.7759/cureus.55153. eCollection 2024 Feb. Cureus. 2024. PMID: 38558653 Free PMC article.
-
Gravity-Dependent Modulation of Downbeat Nystagmus and Subjective Visual Vertical in the Roll Plane.Cerebellum. 2024 Mar 18. doi: 10.1007/s12311-024-01685-y. Online ahead of print. Cerebellum. 2024. PMID: 38499815
-
Vestibulo-spatial navigation: pathways and sense of direction.J Neurophysiol. 2023 Mar 1;129(3):672-684. doi: 10.1152/jn.00422.2022. Epub 2023 Feb 8. J Neurophysiol. 2023. PMID: 36752494 Free PMC article.
-
Movement Disorder in Demyelinating Disease: Tracing the Charcot's Foot Print.Ann Indian Acad Neurol. 2022 Sep-Oct;25(5):821-831. doi: 10.4103/aian.aian_64_22. Epub 2022 Jun 8. Ann Indian Acad Neurol. 2022. PMID: 36561038 Free PMC article.
-
Downbeat Nystagmus in Cerebellitis: The Cerebellar Inhibition to the Vestibulo-Ocular Reflex.Neurol Clin Pract. 2021 Aug;11(4):e585-e586. doi: 10.1212/CPJ.0000000000000951. Neurol Clin Pract. 2021. PMID: 34484967 Free PMC article. No abstract available.
Publication types
MeSH terms
Grants and funding
LinkOut - more resources
Full Text Sources
Medical