doi: 10.1111/j.1365-2141.1978.tb01054.x.
Folate-dependent serine synthesis in lymphocytes from controls and patients with megaloblastic anaemia: the effect of therapy
- PMID: 638084
- DOI: 10.1111/j.1365-2141.1978.tb01054.x
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Folate-dependent serine synthesis in lymphocytes from controls and patients with megaloblastic anaemia: the effect of therapy
Br J Haematol.
1978 Mar.
Abstract
The utilization of [14C]formate for serine synthesis by lymphocytes was impaired in all the patients with pernicious anaemia and in 70% of other patients with megaloblastic anaemia. In pernicious anaemia this was corrected by vitamin B12 therapy in 48 h but not by folate therapy although patients given folate showed a satisfactory haematological response.
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