Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 1983 Nov;44(11 Pt 2):45-57.

Anxiolytic profiles

S Gershon, A S Eison
  • PMID: 6139369
Review

Anxiolytic profiles

S Gershon et al. J Clin Psychiatry. 1983 Nov.

Abstract

The available data from animal and human studies on mechanisms postulated to be involved in the production and mediation of anxiety are reviewed. Effects of specific agents used to treat clinical anxiety, and/or studied in research on experimentally induced behaviors resembling clinical anxiety, are examined in terms of their implications for the etiology and management of these symptoms. In the search for an ideal anxiolytic (i.e., one which would selectively decrease anxiety without producing sedation, cognitive or psychomotor impairment, tolerance/dependence, untoward psychologic reactions, interactions with CNS depressants, or morbidity risk in overdose), recent research has focused on several nonbenzodiazepine substances. Results of these studies indicate that continued study and development of nonbenzodiazepine anxiolytics will facilitate achievement of optimum pharmacotherapeutic approaches to the management of clinical anxiety.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

LinkOut - more resources