Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1970 Jul;23(5):379-91.
doi: 10.1136/jcp.23.5.379.

Megaloblastic anaemia of pregnancy: a clinical and laboratory study with particular reference to the total and labile serum folate levels

P G Rae, P M Robb

Megaloblastic anaemia of pregnancy: a clinical and laboratory study with particular reference to the total and labile serum folate levels

P G Rae et al. J Clin Pathol. 1970 Jul.

Abstract

It has been shown that the incidence of megaloblastic anaemia in a group of 463 randomly selected pregnant women receiving iron was 12 times as high as in a control group of 235 pregnant women receiving iron and folic acid. The incidence of all types of anaemia in the women receiving iron alone was more than three times the incidence in those having iron and folic acid. Some women who were not anaemic or who had normoblastic anaemia had serum folate levels in the same range as the women with megaloblastic anaemia, but none of the women with megaloblastic anaemia had high serum folate levels. The labile fraction of the serum folate was no more reliable than the total serum folate as a diagnostic criterion of megaloblastic erythropoiesis in the individual case. The blood group distribution in the women with megaloblastic anaemia was the same as in the general population. Babies born to mothers with megaloblastic anaemia tended to be smaller than the rest, although there was no difference in the placental weights. The significance of these findings is discussed.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. Lancet. 1966 Jan 1;1(7427):11-4 - PubMed
    1. J Clin Pathol. 1966 Jan;19(1):1-11 - PubMed
    1. Br J Haematol. 1968 Jan;14(1):13-9 - PubMed
    1. Br Med J. 1960 Oct 15;2(5206):1111-4 - PubMed
    1. Lancet. 1960 Nov 12;2(7159):1063-4 - PubMed

LinkOut - more resources