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Case Reports
. 2024 Jan-Mar;34(1):25-28.
doi: 10.4103/jcecho.jcecho_30_22. Epub 2024 Apr 26.

Left Ventricle Noncompaction Phenotype: Cause or Consequence?

Grazia Casavecchia  1 , Matteo Gravina  1 , Francesco Mautone  1 , Maurizio Pesolo  1 , Francesco Mangini  2 , Luca Macarini  1 , Natale Daniele Brunetti  1
Affiliations
Case Reports

Left Ventricle Noncompaction Phenotype: Cause or Consequence?

Grazia Casavecchia et al. J Cardiovasc Echogr. 2024 Jan-Mar.

Abstract

Left ventricular noncompaction (LVNC) is commonly described as a congenital cardiomyopathy characterized by prominent myocardial trabeculae and deep intertrabecular recesses extending in the left ventricular chamber. Clinical presentation can differ considerably from asymptomatic individuals to those presenting with heart failure and other serious complications. Diagnosis is usually made by two-dimensional transthoracic echocardiography or cardiac magnetic resonance. Moreover, even if strain parameters are significantly reduced in patients with LVNC, they are not routinely investigated. Here, we report the case of a previously symptomless patient admitted to the hospital for pulmonary edema. Two-dimensional transthoracic echocardiography showed severe valvular heart disease and left ventricle pronounced trabeculation and remodeling, although speckle tracking echocardiography (STE) demonstrated only mild strain reduction. We, therefore, explore the possibility that STE may be useful to differentiate LVNC cardiomyopathy from LVNC phenotype due to severe remodeling.

Keywords: Athletes; cardiomyopathy; echocardiography; heart failure; left ventricular noncompaction; pregnancy; remodeling; speckle tracking; strain; valvulopathy; ventricular dysfunction.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
(a) Apical 2 chambers showing prominent trabeculation. (b) Short axis view. (c) Contrast-enhanced echocardiography (systole). (d) Three-dimensional echocardiography showing abundant apical trabeculation
Figure 2
Figure 2
(a) Apical 4 chambers showing severe mitral regurgitation. (b) M-mode showing aortic and mitral regurgitation
Figure 3
Figure 3
Bullseye map of left ventricular strain
See this image and copyright information in PMC

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