The association between halitosis and periodontitis: a systematic review and meta-analysis
- PMID: 38801476
- DOI: 10.1007/s00784-024-05732-0
The association between halitosis and periodontitis: a systematic review and meta-analysis
Abstract
Objectives: The purpose of this systemic review and meta-analysis was to explore the association between halitosis and periodontitis in observational studies.
Materials and methods: A systematic search covered PubMed, Web of Science, Embase, Scopus, and Cochrane Library until August 18, 2023. Nine observational studies (585 cases, 1591 controls) were analyzed using Stata 17, with odds ratios (ORs) and 95% confidence intervals (CIs). Subgroup analyses considered halitosis assessment methods.
Results: The review found a positive association between halitosis and periodontitis. Significant differences were observed with organoleptic test (OR = 4.05, 95% CI: 1.76, 9.30, p < 0.01) and volatile sulfur compound readings (OR = 4.52, 95% CI: 1.89, 10.83, p < 0.01).
Conclusions: A positive association was observed between halitosis and periodontitis, supported by significant differences in both organoleptic and volatile sulfur compound readings. However, conclusive findings are limited by statistical heterogeneity, emphasizing the need for additional research.
Clinical relevance: Understanding the halitosis and periodontitis association is clinically significant, informing potential interventions for improved oral health. Further research is vital to refine understanding and guide effective clinical strategies, acknowledging the limitations in current findings.
Keywords: Bad breath; Halitosis; Meta-analysis; Periodontitis.
© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
Similar articles
-
Is periodontitis associated with halitosis? A systematic review and meta-regression analysis.J Clin Periodontol. 2017 Oct;44(10):1003-1009. doi: 10.1111/jcpe.12786. Epub 2017 Aug 25. J Clin Periodontol. 2017. PMID: 28749582 Review.
-
The levels of volatile sulfur compounds in mouth air from patients with chronic periodontitis.J Periodontal Res. 2008 Apr;43(2):186-93. doi: 10.1111/j.1600-0765.2007.01011.x. J Periodontal Res. 2008. PMID: 18302621 Clinical Trial.
-
Investigation of volatile sulfur compound level and halitosis in patients with gingivitis and periodontitis.Sci Rep. 2023 Aug 14;13(1):13175. doi: 10.1038/s41598-023-40391-3. Sci Rep. 2023. PMID: 37580412 Free PMC article.
-
Characteristics of 2000 patients who visited a halitosis clinic.J Clin Periodontol. 2009 Nov;36(11):970-5. doi: 10.1111/j.1600-051X.2009.01478.x. Epub 2009 Oct 6. J Clin Periodontol. 2009. PMID: 19811581
-
The association between halitosis and oral-health-related quality of life: A systematic review and meta-analysis.J Clin Periodontol. 2021 Nov;48(11):1458-1469. doi: 10.1111/jcpe.13530. Epub 2021 Sep 6. J Clin Periodontol. 2021. PMID: 34409629 Review.
References
-
- Hampelska K, Jaworska MM, Babalska Z, Karpiński TM (2020) The role of oral microbiota in intra-oral halitosis. J Clin Med 9:2484. https://doi.org/10.3390/jcm9082484 - DOI - PubMed - PMC
-
- Anbari F, Ashouri Moghaddam A, Sabeti E, Khodabakhshi A (2019) Halitosis: helicobacter pylori or oral factors. Helicobacter 24:e12556. https://doi.org/10.1111/hel.12556 - DOI - PubMed
-
- Tangerman A, Winkel EG (2010) Extra-oral halitosis: an overview. J Breath Res 4:017003. https://doi.org/10.1088/1752-7155/4/1/017003 - DOI - PubMed
-
- Akaji EA, Folaranmi N, Ashiwaju O (2014) Halitosis: a review of the literature on its prevalence, impact and control. Oral Health Prev Dent 12:297–304. https://doi.org/10.3290/j.ohpd.a33135 - DOI - PubMed
-
- Bollen CM, Beikler T (2012) Halitosis: the multidisciplinary approach. Int J Oral Sci 4:55–63. https://doi.org/10.1038/ijos.2012.39 - DOI - PubMed - PMC
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
Research Materials