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Review
. 2024 Jan 15;29(2):411.
doi: 10.3390/molecules29020411.

Decoding Cosmetic Complexities: A Comprehensive Guide to Matrix Composition and Pretreatment Technology

Xiao-Nan Du  1 , Yu He  1 , You-Wen Chen  1 , Qian Liu  1 , Lei Sun  1 , Hui-Min Sun  1 , Xian-Fu Wu  1 , Yong Lu  1
Affiliations
Review

Decoding Cosmetic Complexities: A Comprehensive Guide to Matrix Composition and Pretreatment Technology

Xiao-Nan Du et al. Molecules. .

Abstract

Despite advancements in analytical technologies, the complex nature of cosmetic matrices, coupled with the presence of diverse and trace unauthorized additives, hinders the application of these technologies in cosmetics analysis. This not only impedes effective regulation of cosmetics but also leads to the continual infiltration of illegal products into the market, posing serious health risks to consumers. The establishment of cosmetic regulations is often based on extensive scientific experiments, resulting in a certain degree of latency. Therefore, timely advancement in laboratory research is crucial to ensure the timely update and adaptability of regulations. A comprehensive understanding of the composition of cosmetic matrices and their pretreatment technologies is vital for enhancing the efficiency and accuracy of cosmetic detection. Drawing upon the China National Medical Products Administration's 2021 Cosmetic Classification Rules and Classification Catalogue, we streamline the wide array of cosmetics into four principal categories based on the following compositions: emulsified, liquid, powdered, and wax-based cosmetics. In this review, the characteristics, compositional elements, and physicochemical properties inherent to each category, as well as an extensive overview of the evolution of pretreatment methods for different categories, will be explored. Our objective is to provide a clear and comprehensive guide, equipping researchers with profound insights into the core compositions and pretreatment methods of cosmetics, which will in turn advance cosmetic analysis and improve detection and regulatory approaches in the industry.

Keywords: compositions; cosmetics; detection; personal care products; pretreatment; regulation.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Classification and compositions of cosmetic dosage forms.
Figure 2
Figure 2
Key preservatives utilized in cosmetic formulations.
Figure 3
Figure 3
Principal antioxidants in cosmetic formulations.
Figure 4
Figure 4
Predominant pH adjusters, chelators, and fragrances in cosmetic matrices.
Figure 5
Figure 5
Key oil-based constituents in cosmetic formulations.
Figure 6
Figure 6
Central emulsifying agents in cosmetic preparations.
Figure 7
Figure 7
Prominent humectants and thickeners employed in cosmetic matrices.
See this image and copyright information in PMC

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References

    1. Liang X., Li L., Dong Y., Dong W., Cui H., Xia C., Xu T., Wang C., Zhang J., Liu T., et al. Rapid detection of five estrogens added illegally to dietary supplements by combining tlc with raman imaging microscope. Molecules. 2022;27:2650. doi: 10.3390/molecules27092650. - DOI - PMC - PubMed
    1. Chiari B.G., Almeida M., Corrêa M.A., Isaac V.L.B. Latest Research into Quality Control. InTech; London, UK: 2012. Cosmetics’ quality control; pp. 337–364. - DOI
    1. Su Z., Luo F.-Y., Pei X.-R., Zhang F.-L., Xing S.-X., Wang G.-L. Final publication of the “Regulations on the Supervision and Administration of Cosmetics” and new prospectives of cosmetic science in China. Cosmetics. 2020;7:98. doi: 10.3390/cosmetics7040098. - DOI
    1. Zhang Y., Xie S.-S., Wu Y.-C., Liang Q.-W., Xie X.-T., Luo Z.-H., Liang Z.-H., Liu M.-S. Research progress of detection technology for illegal addition of prohibited substances in cosmetics; Proceedings of the 3rd International Conference on Agricultural and Food Science (ICAFS); Kuala Lumpur, Malaysia. 8–11 December 2020.
    1. Zhan J., Ni M.L., Zhao H.Y., Ge X.M., He X.Y., Yin J.Y., Yu X.J., Fan Y.M., Huang Z.Q. Multiresidue analysis of 59 nonallowed substances and other contaminants in cosmetics. J. Sep. Sci. 2014;37:3684–3690. doi: 10.1002/jssc.201400698. - DOI - PubMed