Identifying and treating iron deficiency anemia in pregnancy
- PMID: 38066889
- PMCID: PMC10727057
- DOI: 10.1182/hematology.2023000474
Identifying and treating iron deficiency anemia in pregnancy
Abstract
Anemia is common during pregnancy, and while most anemia is physiologic, the most common pathologic cause is iron deficiency. The American College of Obstetricians and Gynecologists (ACOG) recommends confirmation of iron deficiency anemia with iron studies when anemia is diagnosed during pregnancy but acknowledges that presumptive treatment for suspected iron deficiency anemia is common in practice. Currently ACOG does not recommend treating iron deficiency without anemia during pregnancy. Though the benefits of treating iron deficiency anemia during pregnancy are clear, the optimal route of iron repletion remains uncertain. Results of ongoing large, randomized trials will help define the optimal route of iron treatment for pregnant patients diagnosed with iron deficiency anemia.
Copyright © 2023 by The American Society of Hematology.
Conflict of interest statement
Adam K. Lewkowitz served on medical advisory boards for Shields Pharmaceutics in 2021 and Pharmacosmos Therapeutics Inc. in 2022.
Methodius G. Tuuli: no competing financial interests to declare.
Similar articles
-
[Review by expert group in the diagnosis and treatment of anemia in pregnant women. Federación Mexicana de Colegios de Obstetricia y Ginecología].Ginecol Obstet Mex. 2012 Sep;80(9):563-80. Ginecol Obstet Mex. 2012. PMID: 23243836 Spanish.
-
Screening for iron deficiency anemia--including iron supplementation for children and pregnant women.Am Fam Physician. 2009 May 15;79(10):897-8. Am Fam Physician. 2009. PMID: 19496390 Review. No abstract available.
-
Protocol for a multicenter, double-blinded placebo-controlled randomized controlled trial comparing intravenous ferric derisomaltose to oral ferrous sulfate for the treatment of iron deficiency anemia in pregnancy: The IVIDA2 trial.Contemp Clin Trials. 2022 Dec;123:106992. doi: 10.1016/j.cct.2022.106992. Epub 2022 Nov 8. Contemp Clin Trials. 2022. PMID: 36368479 Free PMC article.
-
UK guidelines on the management of iron deficiency in pregnancy.Br J Haematol. 2012 Mar;156(5):588-600. doi: 10.1111/j.1365-2141.2011.09012.x. Br J Haematol. 2012. PMID: 22512001
-
Screening, Treatment, and Monitoring of Iron Deficiency Anemia in Pregnancy and Postpartum.J Midwifery Womens Health. 2022 May;67(3):321-331. doi: 10.1111/jmwh.13370. Epub 2022 Jun 1. J Midwifery Womens Health. 2022. PMID: 35642737 Review.
References
-
- World Health Organization. The Global Prevalence of Anaemia in 2011. World Health Organization; 2015.
-
- Stevens GA, Finucane MM, De-Regil LM, et al.. Global, regional, and national trends in haemoglobin concentration and prevalence of total and severe anaemia in children and pregnant and non-pregnant women for 1995-2011: a systematic analysis of population-representative data. Lancet Glob Health. 2013;1:e16-e25. doi:10.1016/S2214-109X(13)70001-9. - DOI - PMC - PubMed
-
- Earl R, Woteki CE, eds. Iron Deficiency Anemia: Recommended Guidelines for the Prevention, Detection, and Management Among US Children and Women of Childbearing Age. Washington, DC: National Academies Press; 1993. - PubMed
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical