Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Nov 29;19(1):252.
doi: 10.1186/s12917-023-03811-0.

An estimation of osteochondrodysplasia prevalence in Australian Scottish Fold cats: a retrospective study using VetCompass Data

Brandon D Velie  1 , Tracey Milden  2 , Hannah Miller  2 , Bianca Haase  3
Affiliations

An estimation of osteochondrodysplasia prevalence in Australian Scottish Fold cats: a retrospective study using VetCompass Data

Brandon D Velie et al. BMC Vet Res. .

Abstract

Background: All Scottish Fold cats are believed to be affected by osteochondrodysplasia, a painful degenerative joint disorder. This retrospective study aimed to estimate the prevalence of osteochondrodysplasia in Scottish Fold and Scottish Straight cats in Australian veterinary clinics using electronic patient records (EPRs), collected between 1992 and 2018.

Results: Consultation events (34,926) in EPRs from veterinary clinics located in New South Wales, Queensland, and Victoria, were collected from 1,131 Scottish Fold and 117 Scottish Shorthair cats. A clinical diagnosis of osteochondrodysplasia was made in 12/1,131 Scottish Fold cats. Additionally, 69 cats were identified with suspected osteochondrodysplasia. Of these, 64 were Scottish Fold and 5 were Scottish Shorthair cats. Male and female cats were equally represented. However, a significant difference was observed for the age clinical signs were first recorded in the EPRs. Cats diagnosed clinically with osteochondrodysplasia were significantly younger (p < 0.0001) compared to cats identified as suspected SFOCD cases.

Conclusions: Findings from this study suggest a relatively low prevalence of clinically diagnosed Scottish Fold osteochondrodysplasia (SFOCD) in the studied Australian Scottish Fold population, with cats generally diagnosed with SFOCD at less than 30 months of age. Further evidence is required to accurately assess the clinical relevance of SFOCD in the Scottish Fold population.

Keywords: Arthritis; Cartilage; Feline; Skeleton.

PubMed Disclaimer

Conflict of interest statement

Bianca Waud (Haase) was associated with CirclePaw, a genetic testing laboratory. The authors declare no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Fig. 1
Fig. 1
Distribution of cats identified as affected or possibly affected by Scottish Fold Osteochondrodysplasia. The total number of individuals included in the analysis is indicated in the centre. Each ring represents the outcome of an analysis with (1) representing the numbers of Scottish Fold cats (blue) and Scottish Shorthair cats (green) included in this study; (2) representing results of the first key word search for SFOCD affected cats. Cats identified as diagnosed with SFOCD are indicated in a dark shade of the phenotype defining colour; (3) representing results of the second key word search for possibly SFOCD affected cats. Cats identified as clinically suspected SFOCD in this analysis are indicated in a second shade of the breed defining colour
Fig. 2
Fig. 2
Age clinically diagnosed SFOCD and clinically suspected SFOCD cats. Age (months) of cats identified as, (A) diagnosed clinically SFOCD and clinically suspected SFOCD; and (B) as diagnosed clinically SFOCD and clinically suspected SFOCD, separated based on recorded ear phenotype; Boxes indicated the 25th and 75th percentiles, the horizontal line denotes the median, and the triangle within the box plot indicates the mean; individuals are indicated as dots
See this image and copyright information in PMC

Similar articles

See all similar articles

References

    1. Malik R, Allan GS, Howlett CR, Thompson DE, James G, McWhirter C, et al. Osteochondrodysplasia in Scottish Fold cats. Aust Vet J. 1999;77(2):85–92. doi: 10.1111/j.1751-0813.1999.tb11672.x. - DOI - PubMed
    1. Takanosu M, Takanosu T, Suzuki H, Suzuki K. Incomplete dominant osteochondrodysplasia in heterozygous Scottish Fold cats. J Small Anim Pract. 2008;49(4):197–199. doi: 10.1111/j.1748-5827.2008.00561.x. - DOI - PubMed
    1. Dyte C, Turner P. Further data on folded-ear cats. Can Genet News1973. p. 112.
    1. Gandolfi B, Alamri S, Darby WG, Adhikari B, Lattimer JC, Malik R, et al. A dominant TRPV4 variant underlies osteochondrodysplasia in Scottish fold cats. Osteoarthr Cartil. 2016;24(8):1441–1450. doi: 10.1016/j.joca.2016.03.019. - DOI - PubMed
    1. Chang J, Jung J, Oh S, Lee S, Kim G, Kim H, et al. Osteochondrodysplasia in three Scottish Fold cats. J Vet Sci. 2007;8(3):307–309. doi: 10.4142/jvs.2007.8.3.307. - DOI - PMC - PubMed

LinkOut - more resources