Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2023 Aug 21;68(8):337-342.
doi: 10.17221/19/2023-VETMED. eCollection 2023 Aug.

Successful treatment of a benign, non-infected cyst in a dog by bone marrow injections

Beata Degorska  1 , Jacek Sterna  1 , Joanna Bonecka  1 , Malgorzata Sobczak-Filipiak  2 , Jowita Jacewicz  1
Affiliations
Case Reports

Successful treatment of a benign, non-infected cyst in a dog by bone marrow injections

Beata Degorska et al. Vet Med (Praha). .

Abstract

Bone cysts are rare orthopaedic problems in dogs. There are no clear treatment guidelines. A young male Shih Tzu was referred to Small Animal Clinic with fifth-degree lameness (5/5) of the left thoracic limb, and with swelling and deformation of the distal humeral region. The radiological assessment revealed an enlargement of the distal brachium and an extensive hypodense osteolytic lesion in the distal metaphyseal region of the humerus. Diagnosis of the bone cyst was formulated and treated with a mini-invasive method using autologous non-concentrated bone marrow injections. The treatment was successful, and at the three weeks, the cyst significantly changed its structure. The follow-up at 12 weeks after the first injection, and at one year revealed complete recovery. To our knowledge, this is the first evidence of a bone cyst in a young dog successfully treated with a minimally-invasive method by using a non-concentrated autologous bone marrow injection.

Keywords: bone defect; bone regeneration; canine; humerus; mini-invasive treatment.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1. Lateral and craniocaudal radiographic view of the left humerus revealed lesions in the metaphyseal region of the distal humerus with enlargement bone outline and thinning cortical bone
Figure 2
Figure 2. Lateral and craniocaudal radiographic view three weeks later
A significantly increased bone density at the bone cyst site without periosteal reaction is visible on the lateral and craniocaudal view of the left humerus
Figure 3
Figure 3. Follow-up radiographs at 12 weeks after the first bone marrow injection
Note correct remodelling of the humerus and cyst healing, and the rapid healing without extensive callus
Figure 4
Figure 4. The control radiographic evaluation one year after the first bone marrow injection
The radiograph shows no abnormalities with normal distal diaphysis of the humerus and normal humeral condyle with superimposed epicondyles
See this image and copyright information in PMC

Similar articles

See all similar articles

References

    1. Barbanti-Brodano G, Girolami M, Ghermandi R, Terzi S, Gasbarrini A, Bandiera S, Boriani S. Aneurysmal bone cyst of the spine treated by concentrated bone marrow: Clinical cases and review of the literature. Eur Spine J. 2017 May;26(Suppl_1):158-66. - PubMed
    1. Barnhart MD. Malignant transformation of an aneurysmal bone cyst in a dog. Vet Surg. 2002 Nov-Dec;31(6):519-24. - PubMed
    1. Bianco P, Robey PG, Simmons PJ. Mesenchymal stem cells: Revisiting history, concepts, and assays. Cell Stem Cell. 2008 Apr 10;2(4):313-9. - PMC - PubMed
    1. Biezynski J, Piatek A, Skrzypczak P, Oginska O, Kielbowicz Z. Operacyjna metoda leczenia cyst kostnych u psow przy uzyciu cementu kostnego [Operating method for treatment of bone cysts in dogs with bone cement]. Med Weter. 2015;71(6):390-2. Polish.
    1. Chahla J, Mannava S, Cinque ME, Geeslin AG, Codina D, LaPrade RF. Bone marrow aspirate concentrate harvesting and processing technique. Arthrosc Tech. 2017 Apr 10;6(2):e441-e5. - PMC - PubMed

Publication types

LinkOut - more resources