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Review
. 2024 Mar;28(1):61-68.
doi: 10.1007/s11325-023-02921-1. Epub 2023 Sep 23.

Influence of nutrition and food on sleep-is there evidence?

Nikolaus C Netzer  1   2   3 , Kingman P Strohl  4 , Stephan Pramsohler  5   6
Affiliations
Review

Influence of nutrition and food on sleep-is there evidence?

Nikolaus C Netzer et al. Sleep Breath. 2024 Mar.

Abstract

Background: The influence of sleep disorders on metabolism, especially concerning obesity and diabetes, as well as obesity and obstructive sleep apnea, has been widely investigated. However, the effect of nutrition and the intake of certain foods on sleep has only recently gained attention. In recent years, there have been publications on intake of certain foods and certain diets regarding their influence on sleep, as well as activity of adipocytes and their effect on production of sleep hormones.

Methods: Following PRISMA guidelines, we performed a PubMed search using the key words "sleep," "sleep disorders," "nutrition," "food," and "food intake" published from 2012 to 2022. We excluded by consensus all articles with diets and exercise programs or bariatric surgery for weight loss to treat sleep apnea, all articles on connections between sleep disorders and metabolic disorders, and articles concerning the influence of drugs on neuroactive substances.

Results: Of the 4155 publications revealed, 988 had nutrition, metabolism, and sleep as the primary topic of research. Of these 988 publications, only 26 fulfilled the content requirements concerning the influence of certain food and diets on sleep or sleep disorders, including the influence of the gastrointestinal system and adipocytes on sleep hormones. None of the investigations revealed clear evidence of an effect of a certain diet or food on sleep. Epidemiologic surveys suggest that shortened or fragmented sleep and chronotype in adults influence nutrition and fat metabolism. Additionally, there is evidence that adipocyte signaling influences neuronal mediators and hormones of the sleep-wake cycle.

Conclusion: There is no evidence of a direct influence of certain nutrition or food intake on sleep. Obesity via adipocyte signaling may influence the sleep-wake cycle, though the molecular research on this topic is based on animal studies.

Keywords: Adipocyte signaling; Food; Melatonin; Nutrition; Sleep; Sleep quality.

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Conflict of interest statement

The authors declare no competing interests.

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