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Review
. 2023 Jul 25:12:191.
doi: 10.4103/abr.abr_251_22. eCollection 2023.

The Best Surgical Treatment for Cervical Radiculopathy: A Systematic Review and Network Meta-Analysis

Afshin Almasi  1 , Samira Jafari  2 , Leila Solouki  2 , Niloofar Darvishi  2
Affiliations
Review

The Best Surgical Treatment for Cervical Radiculopathy: A Systematic Review and Network Meta-Analysis

Afshin Almasi et al. Adv Biomed Res. .

Abstract

A case with an inflamed or damaged nerve root in the cervical spine is defined as cervical radiculopathy.The purpose of the current study is to recognize the most effective surgical procedures in cervical radiculopathy subjects. All related studies were taken using PubMed searching international databases, Scopus, ISI Web of Science (WoS), and Science direct with no limit of until November 20th, 2021. Finally, based on the inclusion and exclusion criteria, after reviewing all randomized controlled trial studies which had the related data the researchers were looking for, they conducted meta-analysis with the seven remaining studies including eight different treatments. Heterogeneity was evaluated by Cochran's Q and Higgins I2 using R software for the network. In the results presented in this study, the neck disability index (NDI) changes as a result of taking cervical anterior discectomy without (ACD) and with fusion (ACDF) and ACD arthroplasty were -0.003, -1.659, and -1.656, respectively. According to the final diagram of the network, 11 comparisons were made in pairs. When each treatment group is compared with ACDF, it is shown that there was a significant mean effect among the patients who receive Mobi-C, Kineflx|C, and ADR, with mean differences of - 8.60 [CI 95% (- 12.75, - 4.45)], - 1.10 [CI 95% (- 5.22, 3.02)], and - 1.00 [CI 95% (- 7.18, 5.18)], respectively. The most effective surgical treatments for cervical radiculopathy were Mobi-c, Kineflx|C, and artificial disc replacement compared to ACDF treatment, respectively.

Keywords: Cervical radiculopathy; meta-analysis; network meta-analysis; surgical procedures.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
The flowchart indicating the steps involved in reviewing the studies included in the systematic review and meta-analysis (PRISMA 2020)
Figure 2
Figure 2
The final network diagram
Figure 3
Figure 3
Meta-analysis study of various surgical treatments for cervical radiculopathy
See this image and copyright information in PMC

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References

    1. Thoomes EJ, van Geest S, van der Windt DA, Falla D, Verhagen AP, Koes BW, et al. Value of physical tests in diagnosing cervical radiculopathy: A systematic review. Spine J. 2018;18:179–89. - PubMed
    1. Choi BW, Kim SS, Lee DH, Kim JW. Cervical radiculopathy combined with cervical myelopathy: Prevalence and characteristics. Eur J Orthop Surg Traumatol. 2017;27:889–93. - PubMed
    1. Klussmann A, Gebhardt H, Liebers F, Rieger MA. Musculoskeletal symptoms of the upper extremities and the neck: A cross-sectional study on prevalence and symptom-predicting factors at visual display terminal (VDT) workstations. BMC Musculoskelet Disord. 2008;9:96. - PMC - PubMed
    1. Lee DH, Park JE, Yoon DM, Yoon KB, Kim K, Kim SH. Factors associated with increased risk for clinical insomnia in patients with postherpetic neuralgia: A retrospective cross-sectional study. Pain Med. 2016;17:1917–22. - PubMed
    1. Cleland JA, Whitman JM, Fritz JM, Palmer JA. Manual physical therapy, cervical traction, and strengthening exercises in patients with cervical radiculopathy: A case series. J Orthop Sports Phys Ther. 2005;35:802–11. - PubMed