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. 2023 Sep 1;142(3):636-639.
doi: 10.1097/AOG.0000000000005285. Epub 2023 Aug 3.

Influenza Vaccination Among Pregnant People Before and During the Coronavirus Disease 2019 (COVID-19) Pandemic

Stephanie A Irving  1 , Bradley Crane, Eric Weintraub, Tia L Kauffman, Neon Brooks, Suchita A Patel, Hilda Razzaghi, Edward A Belongia, Matthew F Daley, Darios Getahun, Sungching C Glenn, Simon J Hambidge, Lisa A Jackson, Elyse Kharbanda, Nicola P Klein, Ousseny Zerbo, Allison L Naleway
Affiliations

Influenza Vaccination Among Pregnant People Before and During the Coronavirus Disease 2019 (COVID-19) Pandemic

Stephanie A Irving et al. Obstet Gynecol. .

Abstract

There are limited data on influenza vaccination coverage among pregnant people in the United States during the coronavirus disease 2019 (COVID-19) pandemic. Within the Vaccine Safety Datalink, we conducted a retrospective cohort study to examine influenza vaccination coverage during the 2016-2017 through the 2021-2022 influenza seasons among pregnant people aged 18-49 years. Using influenza vaccines administered through March each season, we assessed crude coverage by demographic and clinical characteristics. Annual influenza vaccination coverage increased from the 2016-2017 season (63.0%) to a high of 71.0% in the 2019-2020 season. After the start of the COVID-19 pandemic, it decreased to a low of 56.4% (2021-2022). In each of the six seasons, coverage was lowest among pregnant people aged 18-24 years and among non-Hispanic Black pregnant people. The 2021-2022 season had the lowest coverage across all age and race and ethnicity groups. The recent decreases highlight the need for continued efforts to improve coverage among pregnant people.

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Conflict of interest statement

Financial Disclosure Edward A. Belongia's institution received payment from Seqirus. Darios Getahun's institution received payment from Hologic, Inc., Johnson & Johnson, and the NIH/NICHD. Lisa A. Jackson reports research support in the form of grants to her institution from Pfizer in the last 3 years. Nicola P. Klein reports research support in the form of grants to her institution from GlaxoSmithKline, Sanofi Pasteur, Merck, and Pfizer in the last 3 years. Allison L. Naleway reports research support in the form of grants to her institution from Pfizer and Vir Biotechnology in the last 3 years. The other authors did not report any potential conflicts of interest.

Figures

Fig. 1.
Fig. 1.
Influenza vaccination coverage among pregnant people aged 18–49 years, overall and by race and ethnicity, 2016–2017 through 2021–2022 influenza seasons. Eligible pregnancies spanned at least 1 day during the August 1 through March 31 period of an influenza season and met enrollment criteria. All same-season influenza vaccines administered between July 1 and March 31, including before, during, or after pregnancy, were included in coverage estimates.
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