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. 2023 Jul 13;15(14):3125.
doi: 10.3390/nu15143125.

Prevention and Management of Iron Deficiency/Iron-Deficiency Anemia in Women: An Asian Expert Consensus

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Prevention and Management of Iron Deficiency/Iron-Deficiency Anemia in Women: An Asian Expert Consensus

Rishma Dhillon Pai et al. Nutrients. .

Abstract

The lack of standardized clinical practice impeding the optimal management of iron deficiency (ID) and iron deficiency anemia (IDA) in women is a global concern, particularly in the Asia-Pacific region. The aim of this study was to determine best practices through a Delphi consensus process. In Round 1, panelists were asked to rate their level of agreement with 99 statements across four domains: identification, diagnosis and assessment, prevention, and treatment of ID/IDA in women. In Round 2, panelists reappraised their ratings in view of the collective feedback and responses to Round 1. After two rounds, consensus (≥85% agreement) was reached for 84% of the Delphi statements. Experts agreed on the role of presenting symptoms and risk factors in prompting assessments of anemia and iron status in women. Experts repeatedly called for prevention, recommending preventive iron supplementation for pregnant women irrespective of anemia prevalence levels, and for non-pregnant adult women, adolescent girls, and perimenopausal women living in areas with a high prevalence of anemia. Experts unanimously agreed to prescribing oral ferrous iron as first-line therapy for uncomplicated ID/IDA. The recommendations and clinical pathway algorithms generated should be used to inform clinical practice and standardize the care of women at risk or presenting with ID/IDA in the Asia-Pacific region.

Keywords: Delphi; consensus; iron deficiency; iron deficiency anemia; women.

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Conflict of interest statement

The expert panel consensus meeting was organized in association with Procter & Gamble Health. We acknowledge Jass Liew and Vinod Malve, employees of Procter & Gamble Health, for organizing the logistics of the consensus meeting.

Figures

Figure 1
Figure 1
Overview of Delphi survey rounds. * Two statements that did not reach consensus in Round 1 were removed.

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References

    1. Tang C., King K., Ross B., Hamad N. Iron deficiency in women: Clearing the rust of silence. Lancet Haematol. 2022;9:e247–e248. doi: 10.1016/S2352-3026(22)00079-5. - DOI - PubMed
    1. Firquet A., Kirschner W., Bitzer J. Forty to fifty-five-year-old women and iron deficiency: Clinical considerations and quality of life. Gynecol. Endocrinol. 2017;33:503–509. doi: 10.1080/09513590.2017.1306736. - DOI - PubMed
    1. Kinyoki D., Osgood-Zimmerman A.E., Bhattacharjee N.V., Kassebaum N.J., Hay S.I. Anemia prevalence in women of reproductive age in low- and middle-income countries between 2000 and 2018. Nat. Med. 2021;27:1761–1782. doi: 10.1038/s41591-021-01498-0. - DOI - PMC - PubMed
    1. Fernandez-Jimenez M.C., Moreno G., Wright I., Shih P.-C., Vaquero M.P., Remacha A.F. Iron deficiency in menstruating adult women: Much more than anemia. Womens Health Rep. 2020;1:26–35. doi: 10.1089/whr.2019.0011. - DOI - PMC - PubMed
    1. Safiri S., Kolahi A.A., Noori M., Nejadghaderi S.A., Karamzad N., Bragazzi N.L., Sullman M.J.M., Abdollahi M., Collins G.S., Kaufman J.S., et al. Burden of anemia and its underlying causes in 204 countries and territories, 1990–2019: Results from the Global Burden of Disease Study 2019. J. Hematol. Oncol. 2021;14:185. doi: 10.1186/s13045-021-01202-2. - DOI - PMC - PubMed