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. 2023 Dec;37(12):1063-1069.
doi: 10.1038/s41371-023-00849-3. Epub 2023 Jul 22.

Analysis of postpartum hypertension in women with preeclampsia

Qinqin Xue  1 , Guang Li  1 , Yanyun Gao  1 , Yunjing Deng  1 , Bianju Xu  1 , Yu Chen  1 , Yu Gao  1 , Qi Chen  2
Affiliations

Analysis of postpartum hypertension in women with preeclampsia

Qinqin Xue et al. J Hum Hypertens. 2023 Dec.

Abstract

Postpartum hypertension including persistent and recurrent hypertension could significantly affect maternal morbidity in preeclampsia. Data on the postpartum management of women with preeclampsia is limited. The objective of this study was to investigate the details of women experiencing persistent postpartum hypertension (PerPPH) or developing recurrent postpartum hypertension (RecPPH) after birth and whether the treatment with anti-hypertensive drugs could shorten the hospital stay. We also compared the clinical parameters in women who developed RecPPH and who did not. Data on 188 preeclamptic women, including the severity or time of onset, duration of hospital admission postpartum, and blood pressure during the admission were collected and analyzed. Overall, 30% of preeclamptic women developed RecPPH on day 1, 13% on day 3, and 12% on day 5 after birth. Women with severe preeclampsia or early onset preeclampsia are more likely to develop RecPPH, compared to women with mild or late onset preeclampsia. The overall time in days before discharge was not different between women with normal blood pressure and women with abnormal blood pressure 1 h after birth, regardless of the severity or gestation of onset. However, women with severe or early onset preeclampsia stayed longer in the hospital, compared to women with mild or late onset preeclampsia. In addition, women with severe or early onset preeclampsia or early delivery increased risk of developing RecPPH. In conclusion, we demonstrate that RecPPH became apparent on day 1 after delivery, and hence close monitoring of blood pressure even if initially seemingly normal after birth is important.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1. The comparison of days to discharge between the groups.
Kaplan–Meier curve showing the days to discharge was no difference in preeclamptic women with normal and abnormal blood pressure at the time of birth.
Fig. 2
Fig. 2. The comparison of days to discharge between severe and mild preeclampsia.
Kaplan–Meier curve showing the days to discharge was significant longer in severe preeclampsia, compared to mild preeclampsia.
Fig. 3
Fig. 3. The comparison of days to discharge between early onset and late onset preeclampsia.
Kaplan–Meier curve showing the days to discharge was significant longer in early onset preeclampsia, compared to late onset preeclampsia.
See this image and copyright information in PMC

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