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. 2023 Jun 19;41(27):3960-3963.
doi: 10.1016/j.vaccine.2023.05.054. Epub 2023 May 24.

COVID-19 vaccine safety inquiries to the centers for disease control and prevention immunization safety office

Elaine R Miller  1 , Pedro L Moro  2 , Tom T Shimabukuro  2 , Grace Carlock  2 , Shaeyla N Davis  3 , Emma M Freeborn  2 , Amy L Roberts  2 , Julianne Gee  2 , Allan W Taylor  4 , Ruth Gallego  2 , Tiffany Suragh  2 , John R Su  2
Affiliations

COVID-19 vaccine safety inquiries to the centers for disease control and prevention immunization safety office

Elaine R Miller et al. Vaccine. .

Abstract

Background: Following the authorization and recommendations for use of the U.S. COVID-19 vaccines, the Centers for Disease Control and Prevention (CDC)'s Immunization Safety Office (ISO) responded to inquiries and questions from public health officials, healthcare providers, and the general public on COVID-19 vaccine safety.

Methods: We describe COVID-19 vaccine safety inquiries, by topic, received and addressed by ISO from December 1, 2020-August 31, 2022.

Results: Of the 1978 COVID-19 vaccine-related inquiries received, 1655 specifically involved vaccine safety topics. The most frequently asked-about topics included deaths following vaccination, myocarditis, pregnancy, and reproductive health outcomes, understanding or interpreting data from the Vaccine Adverse Event Reporting System (VAERS), and thrombosis with thrombocytopenia syndrome.

Conclusions: Inquiries about vaccine safety generally reflect issues that receive media attention. ISO will continue to monitor vaccine safety inquiries and provide accurate and timely information to healthcare providers, public health officials, and the general public.

Keywords: COVID-19 vaccination; Inquiry response; Vaccine safety.

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Conflict of interest statement

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Fig. 1
Fig. 1
Main inquiry topics received by the CDC Immunization Safety Office, December 2020–August 2022 (N = 642).
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