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Review
. 2023 May 10;24(10):8574.
doi: 10.3390/ijms24108574.

The Role of Vitamins in the Pathogenesis of Asthma

Dominika Zajac  1 , Piotr Wojciechowski  1
Affiliations
Review

The Role of Vitamins in the Pathogenesis of Asthma

Dominika Zajac et al. Int J Mol Sci. .

Abstract

Vitamins play a crucial role in the proper functioning of organisms. Disturbances of their levels, seen as deficiency or excess, enhance the development of various diseases, including those of the cardiovascular, immune, or respiratory systems. The present paper aims to summarize the role of vitamins in one of the most common diseases of the respiratory system, asthma. This narrative review describes the influence of vitamins on asthma and its main symptoms such as bronchial hyperreactivity, airway inflammation, oxidative stress, and airway remodeling, as well as the correlation between vitamin intake and levels and the risk of asthma in both pre- and postnatal life.

Keywords: airway hyperreactivity; airway inflammation; airway remodeling; asthma; maternal intake; oxidative stress; pregnancy; risk of developing asthma; vitamins.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Relationship between vitamins and factors leading to asthma induction (for details, see text). ↓ low; ↑ high/excess; [ox] oxidative stress. Created with BioRender.com.
Figure 2
Figure 2
Factors contributing to asthma control (for details, see text). In green are factors improving asthma control, in red those worsening it. ↓ low/decrease; ↑ high/increase; RTI respiratory tract infections, ICS inhaled corticosteroids, [ox] oxidative stress.
Figure 3
Figure 3
Effects of low vitamin level in asthma and outcomes of the vitamin supplementation (for details, see text). In green are factors improving asthma outcomes, in red those worsening it. ↓ low/decrease; ↑ high/increase; Created with BioRender.com.
See this image and copyright information in PMC

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Grants and funding

This research received no external funding.