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Case Reports
. 2023 Mar 15:35:90-93.
doi: 10.1016/j.jdcr.2023.02.026. eCollection 2023 May.

A case of bullous lesions in cutaneous T-cell lymphoma

Affiliations
Case Reports

A case of bullous lesions in cutaneous T-cell lymphoma

Suzanne Xu et al. JAAD Case Rep. .
No abstract available

Keywords: bullous dermatosis; cutaneous T cell lymphoma; dupilimab; mycosis fungoides; toxic epidermal necrolysis.

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Conflict of interest statement

None disclosed.

Figures

Fig 1
Fig 1
Clinical and histopathologic images of the patient at presentation. A and B, Posterior torso and right anterior leg showing extensive erythematous plaques. C, Atypical lymphocytic infiltrate in epidermis and dermis, hematoxylin-eosin 100×. D-G, Staining for CD3, CD4, CD7, and CD8, 400×.
Fig 2
Fig 2
Clinical images of patient with (A) interval development of erosions of oral mucosa, (B and C) bullae superimposed on erythematous plaques, and (B and D) eroded skin from ruptured bullae.
Fig 3
Fig 3
Histopathological images of lesions of bullous CTCL. A, Subepidermal clefting and large, atypical lymphocytes in the dermis and surrounding adnexal structures with focal epidermotropism, hematoxylin-eosin 100×. B-E, Staining for CD3, CD4, CD7, and CD8 of the underlying dermis of bullous lesions, 400×. F-G, RNA in situ hybridization for IFNG and IL13, 200×. Controls were included for all assays. IFNG, Interferon gamma; IL13, interleukin 13.

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References

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