Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Apr 11;9(3):e61.
doi: 10.1192/bjo.2023.45.

Management of medically assisted withdrawal from alcohol in acute adult mental health and specialist addictions in-patient services: UK clinical audit findings

Affiliations

Management of medically assisted withdrawal from alcohol in acute adult mental health and specialist addictions in-patient services: UK clinical audit findings

Julia Sinclair et al. BJPsych Open. .

Abstract

Background: Medically assisted alcohol withdrawal (MAAW) is increasingly undertaken on acute adult psychiatric wards.

Aims: Comparison of the quality of MAAW between acute adult wards and specialist addictions units in mental health services.

Method: Clinical audit conducted by the Prescribing Observatory for Mental Health (POMH). Information on MAAW was collected from clinical records using a bespoke data collection tool.

Results: Forty-five National Health Service (NHS) mental health trusts/healthcare organisations submitted data relating to the treatment of 908 patients undergoing MAAW on an acute adult ward or psychiatric intensive care unit (PICU) and 347 admitted to a specialist NHS addictions unit. MAAW had been overseen by an addiction specialist in 33 (4%) of the patients on an acute adult ward/PICU. A comprehensive alcohol history, measurement of breath alcohol, full screening for Wernicke's encephalopathy, use of parenteral thiamine, prescription of medications for relapse prevention (such as acamprosate) and referral for specialist continuing care of alcohol-related problems following discharge were all more commonly documented when care was provided on a specialist unit or when there was specialist addictions management on an acute ward.

Conclusions: The findings suggest that the quality of care provided for medically assisted withdrawal from alcohol, including the use of evidence-based interventions, is better when clinicians with specialist addictions training are involved. This has implications for future quality improvement in the provision of MAAW in acute adult mental health settings.

Keywords: Medically assisted alcohol withdrawal; Wernicke's encephalopathy; addictions psychiatry; quality improvement; thiamine.

PubMed Disclaimer

Conflict of interest statement

J.S. is the National Specialty Advisor for Alcohol Dependence to NHS England. C.D. has received funding from the Medical Research Council, the Department of Health and Social Care National Institute for Health and Care Research (NIHR) and the European Commission; he was supported by the NIHR Specialist Biomedical Research Centre for Mental Health at South London and Maudsley NHS Foundation Trust and King's College London, the NIHR Collaboration for Leadership in Applied Health Research and Care at King's College Hospital NHS Foundation Trust and the NIHR Applied Research Collaboration South London (NIHR ARC South London) at King's College Hospital NHS Foundation Trust; he is in receipt of an NIHR Senior Investigator Award. The views expressed are those of the authors and not necessarily those of the NHS, the NIHR or the Department of Health and Social Care. A.L.-H. reports honoraria for speaking engagements and/or attendance at conferences from Lundbeck, Lundbeck Institute UK, Pfizer and Servier; she has received research grants or support from Alcarelle and Lundbeck; she is a member of the British Association for Psychopharmacology and receives honoraria for speaking at educational events and led their ‘addiction’ guidelines, which received support from Archimedes Pharma, Lundbeck, Pfizer and Schering.

Similar articles

References

    1. Castillo-Carniglia A, Keyes KM, Hasin DS, Cerdá M. Psychiatric comorbidities in alcohol use disorder. Lancet Psychiatry 2019; 6: 1068–80. - PMC - PubMed
    1. Bahji A, Bach P, Danilewitz M, Crockford D, el-Guebaly N, Devoe DJ, et al. Comparative efficacy and safety of pharmacotherapies for alcohol withdrawal: a systematic review and network meta-analysis. Addiction 2022; 17: 2591–601. - PMC - PubMed
    1. Martin PR, Singleton CK, Hiller-Sturmhofel S. The role of thiamine deficiency in alcoholic brain disease. Alcohol Res Health 2003; 27: 134–42. - PMC - PubMed
    1. Barnes TRE, Paton C. The Prescribing Observatory for Mental Health 15-Year Report (CCQI 353). Royal College of Psychiatrists, 2020.
    1. National Institute for Health and Care Excellence. Alcohol-Use Disorders: Diagnosis, Assessment and Management of Harmful Drinking (High-Risk Drinking) and Alcohol Dependence (Clinical Guideline CG115). NICE, 2011.