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Case Reports
. 2023 Jan 26:33:59-61.
doi: 10.1016/j.jdcr.2023.01.007. eCollection 2023 Mar.

A rare presentation of cutaneous T-cell lymphoma mimicking morphea

Beverly Yu  1 , Sa Rang Kim  1 , Simon F Roy  1   2 , Michael Girardi  1
Affiliations
Case Reports

A rare presentation of cutaneous T-cell lymphoma mimicking morphea

Beverly Yu et al. JAAD Case Rep. .
No abstract available

Keywords: CD, cluster of differentiation; CTCL, cutaneous T cell lymphoma; MF, mycosis fungoides; T-cell receptor gene rearrangement; cutaneous T-cell lymphoma; histopathology; morphea; mycosis fungoides.

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Conflict of interest statement

None disclosed.

Figures

Fig 1
Fig 1
Cutaneous T-cell lymphoma presenting as indurated plaques. A,Pink indurated plaque on the lower abdomen with peau d’orange changes. B, Violaceous indurated patch without scale on the left breast with sparing of the nipple.
Fig 2
Fig 2
An initial biopsy specimen from the lower abdomen revealed a dense band-like dermal lymphocytic infiltrate without epidermotropism (A, hematoxylin and eosin [H&E], original magnification × 100). A biopsy from the left breast demonstrated nearly identical histopathologic features (B, H&E, original magnification × 100) with a slightly atrophic epidermis and no epidermotropism. The third biopsy specimen obtained 3 years subsequently from a plaque on the left breast showed features consistent with cutaneous T-cell lymphoma (C, H&E, original magnification ×20). A dense lymphocytic infiltrate was present in the superficial and deep dermis. Folliculotropism was demonstrated (C) along with characteristic epidermal extension of monotonous moderately enlarged lymphocytes (D, H&E, original magnification × 100). The reticular dermis showed myxoid alteration of collagen with an interstitial increase in lymphocytes and eosinophils (E, H&E, original magnification × 100).
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References

    1. Girardi M., Heald P.W., Wilson L.D. The pathogenesis of mycosis fungoides. N Engl J Med. 2004;350(19):1978–1988. - PubMed
    1. Lebas E., Collins P., Somja J., Nikkels A.F. A comprehensive update of the atypical, rare and mimicking presentations of mycosis fungoides. Dermatol Ther (Heidelb) 2021;11(6):1931–1951. - PMC - PubMed
    1. Fujimoto M., Basko-Plluska J.L., Petronic-Rosic V., Shea C.R. Early morphea simulating patch-stage mycosis fungoides. Am J Dermatopathol. 2015;37(5):409–412. - PubMed
    1. Basir H.R.G., Alirezaei P., Rezanejad A., Daneshyar S. Early morphea simulating patch-stage mycosis fungoides in two cases. Dermatol Rep. 2018;10(1):7471. - PMC - PubMed
    1. Suchak R., Verdolini R., Robson A., Stefanato C.M. Extragenital lichen sclerosus et atrophicus mimicking cutaneous T-cell lymphoma: report of a case. J Cutan Pathol. 2010;37(9):982–986. - PubMed

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