A primer on cohort studies in vascular surgery research
- PMID: 36414356
- DOI: 10.1053/j.semvascsurg.2022.09.004
A primer on cohort studies in vascular surgery research
Abstract
Vascular research questions can be answered using various study designs. Observational studies are used frequently to address a wide range of clinical questions when randomized clinical trials are not feasible or practical. One of the powerful vascular research tools is the cohort study. The cohort study is a reliable observational study design in which individuals who share a common characteristic (a cohort) are followed over time and their outcomes are assessed at various intervals. This review focuses on the essential characteristics, design, implementation, bias, validity, and clinical significance of cohort studies and provides illustrative examples. A cohort study can be either a prospective or a retrospective study, depending on whether the outcome occurred before or after the enrollment of the cohort. Each type has its advantages and disadvantages. Confounding, selection, and information biases can all occur in cohort studies. Applications of the cohort study design include studying the natural history of a disease, describing a condition's frequency, and investigating multiple outcomes simultaneously.
Copyright © 2022 Elsevier Inc. All rights reserved.
Similar articles
-
Accurate identification of cohort study designs in perinatal research: a practical guide.Am J Obstet Gynecol. 2022 Aug;227(2):231-235.e1. doi: 10.1016/j.ajog.2022.03.014. Epub 2022 Mar 12. Am J Obstet Gynecol. 2022. PMID: 35288086 Clinical Trial.
-
Cohort Studies: Design, Analysis, and Reporting.Chest. 2020 Jul;158(1S):S72-S78. doi: 10.1016/j.chest.2020.03.014. Chest. 2020. PMID: 32658655 Review.
-
Observational designs in clinical multiple sclerosis research: Particulars, practices and potentialities.Mult Scler Relat Disord. 2019 Oct;35:142-149. doi: 10.1016/j.msard.2019.07.006. Epub 2019 Jul 20. Mult Scler Relat Disord. 2019. PMID: 31394404 Review.
-
Clinical Research Methodology 2: Observational Clinical Research.Anesth Analg. 2015 Oct;121(4):1043-1051. doi: 10.1213/ANE.0000000000000861. Anesth Analg. 2015. PMID: 26378704 Review.
-
Overview of the epidemiology methods and applications: strengths and limitations of observational study designs.Crit Rev Food Sci Nutr. 2010;50 Suppl 1(s1):10-2. doi: 10.1080/10408398.2010.526838. Crit Rev Food Sci Nutr. 2010. PMID: 21132580 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
