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Review
. 2023 Feb;103(1):83-92.
doi: 10.1016/j.suc.2022.08.005.

De-Escalating Breast Cancer Therapy

Mary A Varsanik  1 , Sarah P Shubeck  2
Affiliations
Review

De-Escalating Breast Cancer Therapy

Mary A Varsanik et al. Surg Clin North Am. 2023 Feb.

Abstract

The potential value of de-escalation in breast cancer therapy cannot be overstated. From reducing complications and morbidity of surgical therapy to the avoidance of chemotherapy in certain populations, the benefits of eliminating low-value therapies are significant. Further, those interventions that have minimal to no benefit may also further low-risk care cascades resulting in additional treatments or interventions without associated value, with increased financial toxicity, and resulting excess health care expenditures.

Keywords: Breast cancer therapy; Chemotherapy; De-escalation; Surgical management.

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Conflict of interest statement

Disclosure The authors have nothing to disclose.

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