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Review
. 2022 Dec;65(12):1925-1966.
doi: 10.1007/s00125-022-05787-2. Epub 2022 Sep 24.

Management of hyperglycaemia in type 2 diabetes, 2022. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)

Melanie J Davies  1   2 , Vanita R Aroda  3 , Billy S Collins  4 , Robert A Gabbay  5 , Jennifer Green  6 , Nisa M Maruthur  7 , Sylvia E Rosas  8 , Stefano Del Prato  9 , Chantal Mathieu  10 , Geltrude Mingrone  11   12   13 , Peter Rossing  14   15 , Tsvetalina Tankova  16 , Apostolos Tsapas  17   18 , John B Buse  19
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Review

Management of hyperglycaemia in type 2 diabetes, 2022. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)

Melanie J Davies et al. Diabetologia. 2022 Dec.

Abstract

The American Diabetes Association and the European Association for the Study of Diabetes convened a panel to update the previous consensus statements on the management of hyperglycaemia in type 2 diabetes in adults, published since 2006 and last updated in 2019. The target audience is the full spectrum of the professional healthcare team providing diabetes care in the USA and Europe. A systematic examination of publications since 2018 informed new recommendations. These include additional focus on social determinants of health, the healthcare system and physical activity behaviours including sleep. There is a greater emphasis on weight management as part of the holistic approach to diabetes management. The results of cardiovascular and kidney outcomes trials involving sodium-glucose cotransporter-2 inhibitors and glucagon-like peptide-1 receptor agonists, including assessment of subgroups, inform broader recommendations for cardiorenal protection in people with diabetes at high risk of cardiorenal disease. After a summary listing of consensus recommendations, practical tips for implementation are provided.

Keywords: Cardiovascular disease; Chronic kidney disease; Glucose-lowering therapy; Guidelines; Heart failure; Holistic care; Person-centred care; Social determinants of health; Type 2 diabetes mellitus; Weight management.

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Figures

Fig. 1
Fig. 1
Decision cycle for person-centred glycaemic management in type 2 diabetes. Adapted from [5] with permission from Springer Nature, © European Association for the Study of Diabetes and American Diabetes Association, 2018
Fig. 2
Fig. 2
Importance of 24-hour physical behaviours for type 2 diabetes
Fig. 3
Fig. 3
Use of glucose-lowering medications in the management of type 2 diabetes
Fig. 4
Fig. 4
Holistic person-centred approach to T2DM management
Fig. 5
Fig. 5
Place of insulin1
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