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Case Reports
. 2022 Sep 7:15:1263-1267.
doi: 10.2147/JAA.S372928. eCollection 2022.

The Precision Allergy Molecular Diagnosis (PAMD@) in Monitoring the Atopic March in a Child with a Primary Food Allergy: Case Report

Izabela Knyziak-Mędrzycka  1   2 , Monika Szychta  3 , Emilia Majsiak  4 , Andrzej M Fal  2   5   6 , Zbigniew Doniec  7 , Bożena Cukrowska  8
Affiliations
Case Reports

The Precision Allergy Molecular Diagnosis (PAMD@) in Monitoring the Atopic March in a Child with a Primary Food Allergy: Case Report

Izabela Knyziak-Mędrzycka et al. J Asthma Allergy. .

Abstract

The case of a 9-month-old boy with an initial diagnosis of atopic dermatitis and confirmed allergy to hen's egg, cow's milk allergens with episodes of anaphylaxis who developed birch allergy whilst under observation with asthma symptoms was presented. The precision allergy molecular diagnosis (PAMD @) allowed for individualisation of dietary recommendations and observing the early progression of food sensitisation to the main birch molecule. The presented identification of major allergic molecules with PAMD@ in the preclinical phase of asthma contributes to the discussion related to early specific immunotherapy to suppress molecular spread and allergic march. However, more research is needed to verify this hypothesis.

Keywords: PAMD@; allergy; anaphylaxis; atopic march; multiplex molecular tests; sIgE.

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Conflict of interest statement

The authors report no conflicts of interest in this work.

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